POST 122. February 1, 2021. CORONAVIRUS. Dr.Fauci endorses double-masking. Dr.Osterholm disagrees!

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“They say two heads are better than one, but can the same be said for masks?

The answer is yes, according to Dr. Anthony Fauci, the nation’s top infectious disease expert.

“So, if you have a physical covering with one layer, you put another layer on, it just makes common sense that it likely would be more effective,” Fauci told “NBC News’ TODAY” on Monday. “That’s the reason why you see people either double masking or doing a version of an N95.”…

In mid-December, Linsey Marr, a professor of civil and environmental engineering at Virginia Tech who is a leading expert in aerosol transmission of viruses, and Dr. Monica Gandhi, a professor of medicine at UCSF/San Francisco General Hospital, published a commentary calling for double masking,

“For maximal protection,” Marr and Gandhi suggested the public could “wear a cloth mask tightly on top of a surgical mask where the surgical mask acts as a filter and the cloth mask provides an additional layer of filtration while improving the fit.”

A second option, they said, could be to wear a three-layer mask made from a flexible, tightly woven fabric that conforms to the face, with an insert of a “non-woven high-efficiency filter material,” such as a vacuum bag.

Of course, the best facial coverings for protection are the N95-type respirators, made from fibers woven with an electrical charge that can trap errant particles, much like a sock that sticks to a blanket in the dryer. Similar products include the Chinese KN95, the European FFP1 and FFP2 versions, the Australia-New Zealand P2, the Korean 1st Class and the Japanese DS2.

“Consider upgrading from a cloth mask to a surgical mask, or from a surgical mask to an N95/KN95/equivalent if available. Better masks may help reduce risk from more-contagious strains,” former US Centers for Disease and Control director Dr. Tom Friedan tweeted Monday.

But the CDC isn’t currently recommending N95 masks for the general public, partly due to a shortage of the masks for health care workers, and also due to concerns that people will tolerate the masks, which can hinder breathing.

“I worry that if we suggest or require that people wear N95’s they won’t wear them all the time,” Dr. Rochelle Walensky, the new head of the CDC told CNN’s Anderson Cooper and Chief Medical Correspondent Dr. Sanjay Gupta in a town hall Wednesday.”

“They’re very hard to breathe in when you wear them properly,” Walensky said. “They’re very hard to tolerate when you wear them for long periods of time.”” (A)

“A recommendation about double-masking by White House advisor Dr. Anthony Fauci isn’t receiving any praise from one of the nation’s leading experts on COVID-19.

Dr. Michael Osterholm, who leads the Center for Infectious Disease Research and Policy at the University of Minnesota, refuted Dr. Fauci’s claim that double-layering would likely make masking “more effective.”

“I do not support the idea of two masks,” said Dr. Osterholm, who spoke to WCCO Radio’s Cory Hepola on Wednesday morning.

Osterholm explained that masks work based on how they fit and their filtration.

“Masks, as they’re defined work in two ways. The first is in regards to how that masks fits. How well does it fit around you? It’s like swimming goggles. They don’t usually leak through the lenses they leak through the seal around your eyes or face,” said Osterholm.

Dr. Osterholm pointed out the N95 respirators are so highly regarded because of how they filter out the virus.

“They have a very tight face fit and the material that’s used basically for the filters is electrostatically charged,” he said. “The pore size lets air travel through easily, but the virus is trapped as it comes through by an electrostatic charge in the respirator.”

Doubling up on masks would likely lead to more harm, than good, when it comes to cloth face masks, or even N95 respirators.

“If you put more of it on, all it does is it impedes the air coming through and it makes it blow in and out along the sides. The fit becomes even less effective,” Osterholm said. “Double masking could be a detriment to your protection.”  (B)

“The case for wearing a face mask to protect against COVID-19 is strong. According to the latest scientific brief from the Centers for Disease Control and Prevention (CDC), face coverings can reduce the risk of coronavirus infection by more than 70%. But if wearing one face mask offers solid protection, does wearing two masks at the same time work even better? Some people have started “double-masking” to increase their odds of staying COVID-free, and the trend made us wonder what the science says. Here’s what experts told us.

At this time, very little scientific data points to any benefits or drawbacks of wearing more than one face mask, Scott Segal, MD, Thomas H. Irving professor and chair of anesthesiology at Wake Forest Baptist Health in Winston-Salem, North Carolina, tells Health…

One small study directly addresses the benefit of wearing two masks simultaneously, but it hasn’t yet been peer-reviewed (which means the results shouldn’t be used to guide doctors and clinicians yet). In that study, the researchers found that a two-mask “sandwich” might prove better when a higher-functioning mask isn’t available.

“Wearing two masks might be a reasonable idea if the filtration capability of the masks isn’t very strong,” says Dr. Segal.

Most studies, including Dr. Segal’s, have found that multiple layers of cloth filter viral particles better than one single layer, and two layers of high-quality cloth with a tight weave perform best. “With poorer quality materials, more layers may perform better,” Dr. Segal says…

The issue comes down to quality vs. quantity: If a well-fitting, effective face mask isn’t available, then two lesser-quality face masks worn together might improve protection…

Double-masking or adding a filtering material might be the latest pandemic trends, but you don’t need to jump on them just because you see other people doing it. “The consensus is that an appropriate mask is either a surgical mask or a cloth mask that has two layers,” Dr. Krilov says.

Here’s a quick refresher on the best face masks: The CDC recommends choosing a mask that has two or more layers of washable, breathable fabric. It must completely cover your nose and mouth and fit snugly against the sides of your face (no gaps). Don’t wear a mask that’s made of vinyl or another fabric that makes it difficult to breathe. The CDC also advises against a mask with exhalation valves or vents, as these let virus particles escape.” (C)

But while Dr. Anthony Fauci has said it’s “common sense” for people to double-mask right now, most experts say they’re not changing how they mask.

“If you’ve got a decent mask, then the thing you need is something that’s going to make it seal around your nose and your cheeks, under your chin,” University of Maryland virologist Don Milton told Insider. “The best thing is to get one that fits.”

Insider surveyed Milton, along with a dozen other leading public health experts, including doctors, virologists, mask-makers, and environmental engineers. None of them said they are double-masking right now, but that doesn’t mean you shouldn’t. Double-masking can still be useful, especially if you don’t have a mask that filters or fits well.

Dr. Anthony Fauci, the US’ leading infectious disease expert, likes to wear two cloth masks, because he says it’s “more firm and comfortable” than just one, but he says that’s not a choice influenced by rigorous scientific evidence.

“There is no scientific study that I know of,” Fauci told the New York Press Club on Friday, clarifying that his stance on double-masking is a personal one, and not a professional recommendation.

Just because Fauci likes to double-mask doesn’t mean you have to. Many masks on the market are multi-layered, and include filters or special fabrics to trap virus particles inside, making them highly effective.

Double-masking is not always practical, either. Dr. Karen Landers, assistant state health officer at the Alabama Department of Public Health, experimented with double-masking: wearing a cotton mask on top of a surgical mask (which is the way that most experts would recommend) — but it didn’t go smoothly. 

“By the time I adjusted it, and accounted for bunching, and for the difficulty of really keeping it positioned in place, I decided that if I had trouble doing it, that perhaps this was not a good strategy to advise the general public,” Landers said.

This is why Landers stresses that wearing one mask that fits correctly is better than wearing two masks.

“If we start going into a strategy of wearing two masks, that is really not, in my opinion, better than wearing an appropriately constructed, layered mask that is correctly fitted and consistently worn.””  (D)

Links to POSTS 1-121

CORONAVIRUS TRACKING

Links to POSTS 1-121

Doctor, Did You Wash Your Hands?®

https://doctordidyouwashyourhands.com/

Curated Contemporaneous Case Study Methodology

Jonathan M. Metsch, Dr.P.H.

https://www.mountsinai.org/profiles/jonathan-m-metsch

PART 1. January 21, 2020. CORONAVIRUS. “The Centers for Disease Control and Prevention on Tuesday confirmed the first U.S. case of a deadly new coronavirus that has killed six people in China.”

PART 2. January 29, 2020. CORONAVIRUS. “If it’s not contained shortly, I think we are looking at a pandemic..”….. “With isolated cases of the dangerous new coronavirus cropping up in a number of states, public health officials say it is only a matter of time before the virus appears in New York City.”

PART3. February 3, 2020. “The Wuhan coronavirus spreading from China is now likely to become a pandemic that circles the globe…”..Trump appeared to downplay concerns about the flu-like virus …We’re gonna see what happens, but we did shut it down..” (D)

PART 4. February 9, 2020. Coronavirus. “A study published Friday in JAMA found that 41% of the first 138 patients diagnosed at one hospital in Wuhan, China, were presumed to be infected in that hospital.….

PART 5. February 12, 2020. CORONAVIRUS. “In short, shoe-leather public health and basic medical care—not miracle drugs—are generally what stop outbreaks of emerging infections..”

POST 6. February 18, 2020.  Coronovirus. “Amid assurances that the (ocean liner) Westerdam was disease free, hundreds of people disembarked in Cambodia…” “ One was later found to be infected”…. “Over 1,000… passengers were in…transit home”…. “This could be a turning point””

PART 7. February 20, 2020. CORONAVIRUS. With SARS preparedness underway in NJ LibertyHealth/ Jersey City Medical Center, where I was President, proposed that our 100 bed community hospital with all single-bedded rooms, be immediately transformed into an EMERGENCY SARS ISOLATION Hospital.

PART 8. February 24, 2020. CORONAVIRUS. “…every country’s top priority should be to protect its health care workers. This is partly to ensure that hospitals themselves do not become sites where the coronavirus is spread more than it is contained.”

PART 9. February 27, 2020. CORONAVIRUS. Responding to a question about the likelihood of a U.S. outbreak, President Trump said, “I don’t think it’s inevitable…”It probably will. It possibly will,” he continued. “It could be at a very small level, or it could be at a larger level.”

Part 10. March 1, 2020. CORONAVIRUS. Stop Surprise Medical Bills for Coronavirus care. (&) Lessons Learned (or not) In California and Washington State from community acquired cases.

PART 11. March 5, 2020.  CORONAVIRUS. “Gov. Andrew Cuomo… would require employers to pay workers and protect their jobs if they are quarantined because of the coronavirus.”

Part 12. March 10, 2020. CORONAVIRUS. “Tom Bossert, Donald Trump’s former homeland security advisor…(said) that due to the coronavirus outbreak, “We are 10 days from the hospitals getting creamed.”

Part 13.. March 14, 2020. CORONAVIRUS. “If I’m buying real estate in New York, I’ll listen to the President….If I’m asking about infectious diseases, I’m going to listen to Tony Fauci,”

PART 14. March 17, 2020. CORONAVIRUS. “ “Most physicians have never seen this level of angst and anxiety in their careers”…. One said “I am sort of a pariah in my family.”

PART 15. March 22, 2020. CORONAVIRUS. “…Crimson Contagion” and imagining an influenza pandemic, was simulated by the Trump administration….in a series of exercises that ran from last January to August.

PART 16. March 27, 2020. CORONAVIRUS. I am not a clinician or a medical ethicist but articles on Coronavirus patient triage started me Googling………to learn about FUTILE TREATMENT

PART 17. April 2, 2020. CORONAVIRUS. Florida allows churches to continue holding services. Gun stores deemed “essential.”  “New York’s private and public hospitals unite to manage patient load and share resources.

PART 18. April 9, 2020. CORONAVIRUS. “The federal government’s emergency stockpile of personal protective equipment (PPE) is depleted, and states will not be receiving any more shipments, administration staff told a House panel.

PART 19. April 13, 2020 CORONOAVIRUS. “…overlooked in the United States’ halting mobilization against the novel coronavirus: the personal aides, hospice attendants, nurses and occupational or physical therapists who deliver medical or support services to patients in their homes.”

PART 20. April 20, 2020. CORONAVIRUS. “…nothing is mentioned in the “Opening Up America Again” plan about how states should handle a resurgence.”

PART 21. April 23, 2020. CORONAVIRUS. “We need to ask, are we using ventilators in a way that makes sense for other diseases but not this one?”

POST 22. April 29, 2020. CORONAVIRUS. ..the “ACS released a list of 10 issues that should be addressed before a healthcare organization resumes elective surgeries[JM1] ….”

POST 23. May 3, 2020. CORONAVIRUS. … what Dr. Fauci really wants,…”is just to go to a baseball game. That will have to wait. The level of testing for the virus is not adequate enough to allow for such mass gatherings.’ (K)

POST 24. May 7, 2020. CORONAVIRUS. Former New Jersey governor Chris Christie said: “there are going to be deaths no matter what”… but that people needed to get back to work.

POST 25. May 10, 2020, CORONAVIRUS. “It is scary to go to work,” said Kevin Hassett, a top economic adviser to the president. “I think that I’d be a lot safer if I was sitting at home than I would be going to the West Wing.”

POST 26. May 14, 2020. CORONAVIRUS, “Deep cleaning is not a scientific concept”….”there is no universal protocol for a “deep clean” to eradicate the coronavirus”

POST 27. May 19, 2020. CORONAVIRUS. “Hospital…executives…are taking pay cuts…to help offset the financial fallout from COVID-19.” As “front line” layoffs and furloughs accelerate…

POST 28. May 23, 2020. CORONAVIRUS. ““You’ve got to be kidding me,”..”How could the CDC make that mistake? This is a mess.” CDC conflates viral and antibody tests numbers.

PART 29. May 22, 2020. CORONAVIRUS. “The economy did not close down. It closed down for people who, frankly, had the luxury of staying home,” (Governor Cuomo). But not so for frontline workers!

POST 30. June 3,202. CORONAVIRUS. “The wave of mass protests across the United States will almost certainly set off new chains of infection for the novel coronavirus, experts say….

POST 31. June 9, 2020. CORONAVIRUS. “I think we had an unintended consequence: I think we made people afraid to come back to the hospital,”

Post 32. June 16, 2020. CORONAVIRUS. Could the Trump administration be pursuing herd immunity by “inaction”?  “ If Fauci didn’t exist, we’d have to invent him.”

POST 33. June 21, 2002. CORONAVIRUS….. Smashing (lowering the daily number of cases) v. flattening the curve (maintaining a plateau)

POST 34. June 26, 2020. CORONAVIRUS. CDC Director Redfield… “the number of coronavirus infections…could be 10 times higher than the confirmed case count — a total of more than 20 million.” As Florida, Texas and Arizona become eipicenters!

POST 35. June 29, 2020. CORONAVIRUS. Pence: “We slowed the spread. We flattened the curve. We saved lives..”  While Dr. Fauci “warned that outbreaks in the South and West could engulf the country…”

POST 36. July 2, 2020. CORONAVIRUS. “There’s just a handful of interventions proven to curb the spread of the coronavirus. One of them is contact tracing, and “it’s not going well,” (Dr. Anthony Fauci)..

POST 37. June 8, 2020. CORONAVIRUS. When “crews arrive at a hospital with a patient suspected of having COVID-19, the hospital may have a physical bed open for them, but not enough nurses or doctors to staff it.”

POST 38. July 15, 2020. CORONAVIRUS. Some Lessons Learned, or not. AdventHealth CEO Terry Shaw: I wouldn’t hesitate to go to Disney as a healthcare CEO — based on the fact that they’re working extremely hard to keep people safe,” (M)

POST 39. July, 23,2020. CORONAVIRUS. A Tale of Two Cities. Seattle becomes New York (rolls back reopening) while New York becomes Seattle (moves to partial phase 4 reopening)

POST 40. July 27, 2020. CORONAVIRUS.” One canon of medical practice is that you order a test only if you can act on the result. And with a turnaround time of a week or two, you cannot. What we have now is often not testing — it’s testing theater.”

POST 41. August 2, 2020. CORONAVIRUS. “Whenever a vaccine for the coronavirus becomes available, one thing is virtually certain: There won’t be enough to go around. That means there will be rationing.”

POST 42. August 11, 2020. CORONAVIRUS. “I think that if future historians look back on this period, what they will see is a tragedy of denial….

POST 43. August 22, 2020. CORONAVIRUS.”  “we’ve achieved something great as a nation. We’ve created an unyielding market for FAUCI BOBBLEHEADS”!! (W)

POST 44.  September 1, 2020. CORONAVIRUS. “The CDC…modified its coronavirus testing guidelines…to exclude people who do not have symptoms of Covid-19.” (While Dr. Fauci was undergoing surgery.) A White House official said: “Everybody is going to catch this thing eventually..”

POST 45. September 9, 2020. CORONAVIRUS.  Trump on Fauci. ‘You inherit a lot of people, and you have some you love, some you don’t. I like him. I don’t agree with him that often but I like him.’

POST 46.  September 17, 2020. CORONAVIRUS. “Bill Gates used to think of the US Food and Drug Administration as the world’s premier public-health authority. Not anymore. And he doesn’t trust the Centers for Disease Control and Protection either….”

POST 47. September 24, 2020. CORONAVIRUS. “Perry N. Halkitis, dean of the School of Public Health at Rutgers University…called New York City’s 35 percent rate for eliciting contacts “very bad.” “For each person, you should be in touch with 75 percent of their contacts within a day,” he said”

POST 48. October 1, 2020.   “…you can actually control the outbreak if you do the nonpharmaceutical interventions (social distancing and masks). In the United States we haven’t done them. We haven’t adhered to them; we’ve played with them.” (A)

POST 49. October 4, 2020. CORONAVIRUS. RAPID RESPONSE. “The possibility that the president and his White House entourage were traveling superspreaders is a nightmare scenario for officials in Minnesota, Ohio, New Jersey and Pennsylvania…”

POST 50. October 6, 2020. CORONAVIRUS. Monday October 5th will go down as one of the most fraught chapters in the history of American public Health (and national security).

POST 51. October 12, 2020. Rather than a hodge-podge of Emergency Use Authorizations, off-label “experimentation”, right-to-try arguments, and “politicized” compassionate use approvals maybe we need to designate REGIONAL EMERGING VIRUSES REFERRAL CENTERS (REVRCs).

POST 52. October 18, 2020.  ZIKA/ EBOLA/ CANDIDA AURIS/ SEVERE FLU/ Tracking. “… if there was a severe flu pandemic, more than 33 million people could be killed across the world in 250 days… Boy, do we not have our act together.” —”- Bill Gates. July 1, 2018

POST 53. October 20, 2020. CORONAVIRUS. “a…“herd-immunity strategy” is a contradiction in terms, in that herd immunity is the absence of a strategy.”

POST 54. October 22, 2020. CORONAVIRUS. POST 54A. New Jersey’s Coronavirus response, led by Governor Murphy and Commissioner of Health Persichilli started with accelerated A+ traditional, evidence-based Public Health practices, developed over years of experience with seasonal flu, swine flu, Zika, and Ebola.

POST 55. October 26, 2020. CORONAVIRUS. The Testing Conundrum: “ It’s thus very possible to be antigen negative but P.C.R. positive, while still harboring the virus in the body..”

Post 56. October 30, 2020. CORONAVIRUS. “Trump’s now back in charge. It’s not the doctors.”

POST 57. November 3, 2020. CORONAVIRUS. Dr. Deborah Birx: the US is entering its “most deadly phase” yet, one that requires “much more aggressive action,”

POST 58. November 4, 2020. CORONAVIRUS. “…the president has largely shuttered the White House Coronavirus Task Force and doubled down on anti-science language…”

POST 59. November 5, 2020. Coronavirus. “The United States on Wednesday recorded over 100,000 new coronavirus cases in a single day for the first time since the pandemic began..

POST 60. November 7, 2020. “White House chief of staff Mark Meadows has tested positive for the coronavirus….” (A)

POST 61. November 7, 2020. CORONAVIRUS. “Joe Biden’s top priority entering the White House is fighting both the immediate coronavirus crisis and its complex long-term aftermath…” “Here are the key ways he plans to get US coronavirus cases under control.”

POST 62. November 8, 2020. CORONAVIRUS. “The United States reported its 10 millionth coronavirus case on Sunday, with the latest million added in just 10 days,…”

POST 63. November 9, 2020. CORONAVIRUS. “New York City-based Mount Sinai Health System has opened a center to help patients recovering from COVID-19 and to study the long-term impact of the disease….”

POST 64. November 10, 2020. CORONAVIRUS. “It works! Scientists have greeted with cautious optimism a press release declaring positive interim results from a coronavirus vaccine phase III trial — the first to report on the final round of human testing.”

POST 65. November 11, 2020. CORONAVIRUS, “The Centers for Disease Control and Prevention took a stronger stance in favor of masks on Tuesday, emphasizing that they protect the people wearing them, rather than just those around them…

POST 66. November.12, 2020. CORONAVIRUS.”… as the country enters what may be the most intense stage of the pandemic yet, the Trump administration remains largely disengaged.”… “President-elect Biden has formed a special transition team dedicated to coordinating the coronavirus response across the government…”

POST 67. November 13, 2020. CORONAVIRUS. “When all other options are exhausted, the CDC website says, workers who are suspected or confirmed to have COVID-19 (and “who are well enough to work”) can care for patients who are not severely immunocompromised — first for those who are also confirmed to have COVID-19, then those with suspected cases.”

POST 68. November 14, 2020. CORONAVIRUS. The CDC “now is hewing more closely to scientific evidence, often contradicting the positions of the Trump administration.”..” “A passenger aboard the first cruise ship to set sail in the Caribbean since the start of the pandemic has tested positive for coronavirus..”

POST 69. November 15, 2020. CORONAVIRUS. “Colorado Gov. Jared Polis will issue a new executive order outlining steps hospitals will need to take to ready themselves for a surge in COVID-19 hospitalizations and directing the hospitals to finalize plans for converting beds into ICU beds, adding staffing and scaling back on or eliminating elective procedures….

POST 70. November 16, 2020. CORONAVIRUS. “White House coronavirus task force member Dr. Atlas criticized Michigan’s new Covid-19 restrictions..urging people to “rise up” against the new public health measures.

POST 71. November 17, 2020. CORONAVIRUS. ”Hospitals overrun as U.S. reports 1 million new coronavirus cases in a week.” “But in Florida, where the number of coronavirus infections remains the third-highest in the nation, bars and schools remain open and restaurants continue to operate at full capacity.”

POST 72. November 18, 2020. CORONAVIRUS. “The Health and Human Services Department will not work with President-elect Joe Biden’s (PANDEMIC) team until the General Services Administration makes a determination that he won the election,….”

POST 73. November 19, 2020. CORONAVIRUS. “…officials at the CDC…urged Americans to avoid travel for Thanksgiving and to celebrate only with members of their immediate households…” When will I trust a vaccine? to the last question I always answer: When I see Tony Fauci take one….”

POST 74. November 20, 2020. CORONAVIRUS. Pfizer…submitted to the FDA for emergency use authorization for their coronavirus vaccine candidate. —FDA issued an EUA for the drug baricitinib, in combination with remdesivir, as WHO says remdesivir doesn’t do much of anything.

POST 75. November 21, 2020. CORONAVIRUS. “The president and CEO of one of the nation’s largest non-profit health systems says he won’t be wearing a mask at work because he’s recovered from COVID-19, and doing so would only be a “symbolic gesture” because he considers himself immune from the virus….

POST 76. November 23, 2020. CORONAVIRUS. “No battle plan survives contact with the enemy.” Ventilators..”just keep people alive while the people caring for them can figure out what’s wrong and fix the problem. And at the moment, we just don’t have enough of those people.”

POST 77. November 26, 2020. CORONAVIRUS. Pope Francis: “When I got really sick at the age of 21, I had my first experience of limit, of pain and loneliness.”.. “….Aug. 13, 1957. I got taken to a hospital…”….” I remember especially two nurses from this time.”…” They fought for me to the end, until my eventual recovery.”

POST 78. November 27, 2020. CORONAVIRUS. “Kelby Krabbenhoft is no longer president and CEO of Sioux Falls, S.D.-based Sanford Health.” “…for not wearing a face covering… “ because “He considered himself immune from the virus.”

POST 79. November 28, 2020. CORONAVIRUS. Mayo Clinic. “”Our surge plan expands into the garage…”..””Not where I’d want to put my grandfather or my grandmother,” … though it “may have to happen.”

POST 80. November 29, 2020. CORONAVIRUS. Op-Ed in the Jersey Journal. Do you know which hospital is right for you if you have coronavirus? | Opinion

POST 81. December 1, 2020. CORONAVIRUS. “Dr. Atlas, … who espoused controversial theories and rankled government scientists while advising President Trump on the coronavirus pandemic, resigned…”

POST 82. December 3, 2020. CORONAVIRIUS. The NBA jumped to the front of the line for Coronavirus testing….while front line nurses often are still waiting. Who will similarly “hijack” the vaccine?

POST 83. December 4, 2020. CORONAVIRUS. “California Gov. Gavin Newsom says he will impose a new, regional stay-at-home order for areas where capacity at intensive care units falls below 15%.”… East Tennessee –“This is the first time the health care capability benchmark has been in the red..”

POST 84. December 6, 2020. CPRONAVIRUS. “ More than 100,000 Americans are in the hospital with COVID-19…” “We’re seeing C.D.C. …awaken from (its) politics-induced coma…”…Dr. Fauci “to be a chief medical adviser in Biden’s incoming administration..”.. “Trump administration leaves states to grapple with how to distribute scarce vaccines..”

POST 85. December 7, 2020. CORONAVIRUS. “…Florida, Gov. DeSantis’ administration engaged in a pattern of spin and concealment that misled the public on the gravest health threat the state has ever faced..”.. “NY Gov. Cuomo said…the state will implement a barrage of new emergency actions..”… Rhode Island and Massachusetts open field hospitals… “Biden Names Health Team to Fight Pandemic”

POST 86. December 9, 2020. If this analysis seems a bit incomprehensible it is because “free Coronavirus test” is often an oxymoron! with charges ranging from as little as $23 to as much as $2,315… Laws (like for free Coronavirus tests) are Like Sausages. Better Not to See Them Being Made. (Please allow about 20 seconds for the text to download. Thanx!)

POST 87. December 10, 2020. CORONAVIRUS. “…Rudolph W. Giuliani, the latest member of President Trump’s inner circle to contract Covid-19, has acknowledged that he received at least two of the same drugs the president received. He even conceded that his “celebrity” status had given him access to care that others did not have.”

POST 88. December 11, 2020. CORONAVIRUS. “As COVID-19 cases surge, the federal government is releasing data about hospital capacity at facilities around the country….”The new data paints the picture of how a specific hospital is experiencing the pandemic,”…

PART 89. December 12, 2020. CORONAVIRUS. THE VACCINE!!! “Now this is not the end. It is not even the beginning of the end. But it is, perhaps, the end of the beginning.” Winston Churchill

POST 90. December 14, 2020. CORONAVIRUS. “…the first doses of a Covid-19 vaccine have been given to the American public..”…” Each person who receives a vaccine needs two doses, and it’s up to states to allocate their share of vaccines.”

POST 91. December 15, 2020. CORONAVIRUS. “UPMC will first give (vaccination) priority to those in critical jobs. That includes a range of people working in critical units, from workers cleaning the emergency room and registering patients to doctors and nurses.. “Finally, if needed, UPMC will use a lottery to select who will be scheduled first.”

POST 92. December 17, 2020. CORONAVIRUS. “..each state — and each hospital system — has come up with its own (vaccination) plan and priorities. The result has been a sometimes confusing constellation of rules and groupings that has left health care workers wondering where they stand.” (Trump appointee July 4th email “…we need to establish herd, and it only comes about allowing the non-high risk groups expose themselves to the virus. PERIOD,”)

POST 93. December 19, 2020. CORONAVIRUS.  On NPR Congresswoman Shalala (D-Florida) said she wouldn’t jump the vaccination line in Miami; then added she would get vaccinated in Washington this week. This, even though Congress has failed to pass “essential” Coronavirus legislation. So who are our “essential” workers?

POST 94. December 21, 2020. CORONAVIRUS. “A doctor at an L.A. County public hospital said the number of COVID-19 patients is “increasing exponentially, without an end in sight.”.. “I haven’t done ICU medicine since I was a resident — you don’t want me adjusting your ventilator,” he said. “That’s the challenge, actually — it isn’t so much space, it’s staff…”

POST 95. December 23, 2020. “The Murphy administration may step in to force (New Jersey) hospitals to report COVID-19 outbreaks among staff.”

POST 96. December 26, 2020. CORONAVIRUS. “Achieving herd immunity against the coronavirus could require as much as 90 percent of the population to be vaccinated, Anthony Fauci…”…”..he hesitated to state a number as high as 90% weeks ago because many Americans still seemed skeptical about vaccine….”

POST 97. December 27, 2020. “A new variant of the coronavirus that has been spreading through the UK and other countries has not yet been detected in the United States..”.. . But if new-wave medicines like antivirals and antibody therapy contributed to the development of viral variants, it will be “a reminder for all the medical community that we need to use these treatment options carefully.”

POST 98. December 28, 2020. CORONAVIRUS. “Governor Andrew Cuomo announced new penalties in order to rein in possible vaccination fraud…

POST 99. December 29, 2020. CORONAVIRUS. “ICUs are being overwhelmed across many parts of California. Statewide aggregate ICU availability has been at 0% since Christmas Eve…. a surge on top of a surge on top of a surge.”… “hospitals are getting close to the point where they would begin putting COVID-positive patients under the care of COVID-positive staff who are asymptomatic.”

POST 100. December 29, 2020. CORONAVIRUS. Front line hospital workers – in the ER, ICUs, EMS, acute medical care, behavioral health – are amongst the most courageous, heroic and dedicated colleagues you will ever meet.

POST 101. December 30, 2020.CORONAVIRUS. Is there a point where the increasing Coronavirus trajectory so far exceeds the slow growth of the vaccination rate that reaching herd immunity through vaccinations becomes less likely?

POST 102. January 2, 2020. CORONAVIRUS. “We’ve taken the people with the least amount of resources and capacity and asked them to do the hardest part of the vaccination — which is actually getting the vaccines administered into people’s arms,” said Dr. Ashish Jha, the dean of Brown University’s School of Public Health. “Ultimately, the buck seems to stop with no one,”…

POST 103. January 4, 2021. CORONAVIRUS. Dr. Fauci said “that the United States would not follow Britain’s lead in front-loading first vaccine injections, potentially delaying the administration of second doses…Dr. Moore – ”British officials “seem to have abandoned science completely now and are just trying to guess their way out of a mess.”

POST 104. January 6, 2021. CORONAVIRUS. “Paramedics in Southern California are being told to conserve oxygen and not to bring patients to the hospital who have little chance of survival…”

POST 105. January 8, 2021. CORONAVIRUS. POST 105. January 8, 2021. CORONAVIRUS. “Facing a shortage of vaccinators, the Association of Immunization Managers… recommends relaxing regulation or adjusting licensing requirements. At least two states, Massachusetts and New York, have changed their laws in recent weeks to expand those who are eligible to give shots.”

POST 106. January 9, 2021. CORONAVIRUS. The riots at the Capitol could have been a superspreader event. “From what I saw… you had a large congregation of individuals who were in close contact for an extended period of time and almost universally unmasked…. many coming and going on buses as well, also unmasked, and hanging out in hotel lobbies.”

POST 107. January 8, 2021. CORONAVIRUS. “Our job is to make sure the vaccine isn’t politicized the way masks were politicized,” Rep. Alexandria Ocasio-Cortez, D-N.Y., said after getting her vaccine.   South Carolina Rep.-elect Nancy Mace, a Republican, wrote that “Congress shouldn’t be putting themselves first in line for the COVID-19 vaccination when the average American can’t get it.”

POST 108. January 9, 2021. CORONAVIRUS. (vaccination)”Line-cutters will be named and shamed. It’s inevitable, as will be the congressional hearings and front-page investigative stories ferreting out who saved their own skin at the expense of others.” 

POST 109.January 9, 2021. CORONAVIRUS. “President-elect Joe Biden will aim to release nearly every available dose of the coronavirus vaccine when he takes office, a break with the Trump administration’s strategy of holding back half of US vaccine production to ensure second doses are available.

POST 110. January 13, 2021. CORONAVIRUS. ““The (federal) government is changing the way it allocates Covid vaccine doses, now basing it on how quickly states can administer shots and the size of their elderly population.”… “New York State sent a letter to hospitals saying if they don’t use their vaccine allocations by the end of this week, they won’t receive any further allocations.”

POST 111. January 14, 2021. CORONAVIRUS. “Visitors from Toronto to New York to Buenos Aires have long flocked to Florida for sun, surf and shopping. Now they are coming for the Covid-19 vaccine….

POST 112. January 14, 2021. CORONAVIRUS. CHINA – “Eleven million people are under lockdown in Hebei province after a new cluster of coronavirus infections.

PART 113. January 17, 2021. CORONAVIRUS. The Next President Actually Has a Covid Plan… New York City and other places in the state expect to exhaust their supply of doses as early as next week… Charles Barkley said during the “NBA on TNT” broadcast that pro athletes should get the first round of the vaccine…..

POST 114. January 18, 2021. CORONAVIRUS. “When government programs that have been unattended, underfunded and bogged down by red tape suddenly have to meet a huge demand in a crisis, they can’t cope and people suffer….”

POST 115. January 21, 2020. CORONAVIRUS. A year ago today an unnumbered POST was headlined “The Centers for Disease Control and Prevention on Tuesday confirmed the first U.S. case of a deadly new coronavirus that has killed six people in China.” The CORONAVIRUS CONTENT TRACKING PROJECT started with HISTORIOGRAPHY and over time moved to LESSONS LEARNED, RAPID RESPONSE, and THE VACCINATION PROGRAM. Now 115 POSTS later – the BIDEN CORONAVIRUS PLAN.

POST 116. January 22, 2021. President Biden – “We’re entering what may be the toughest and deadliest period of the virus. We must set aside politics and finally face this pandemic as one nation.”

POST 117. January 23, 2021. CORONAVIRUS. 1.Dr. Fauci:“The idea that you can get up here….”and.. let the science speak”… “It is somewhat of a liberating feeling.” 2.updated CDC guidance:”.. providers could give the second dose up to six weeks after the first dose..” 3.Dr. Fauci: people would be “taking a chance” if they follow the CDC’s updated guidance.

POST 118. January 24, 2021. CORONAVIRUS. “Unfortunately, we’ve let this virus spread extensively and are launching the vaccination campaign at the height of the threat,” Dr. Meyers said. “The more the virus spreads before the vaccine reaches people, the fewer deaths we can prevent with the vaccine.”

POST 119. January 27, 2010. CORONAVIRUS. Amazon is offering its help to President Joe Biden with the rollout of COVID-19 vaccines. Washington’s governor, Jay Inslee, included the help of companies like Starbucks, Costco and Microsoft in a plan to vaccinate 45,000 residents a day.

POST 120. January 28, 2021. CORONAVIRUS. “The fact that four vaccines backed by the federal government seem to be less effective against the (South African) B.1.351 variant has unsettled federal officials and vaccine experts alike. Facing this uncertainty, many researchers said it was imperative to get as many people vaccinated as possible — quickly. Lowering the rate of infection could thwart the contagious variants while they are still rare, and prevent other viruses from gaining new mutations that could cause more trouble.”

POST 121. January 30, 2021. CORONVIRUS. Will our communities become stratified by which vaccine is distributed? 95%ters v. 72%ters? Will the easier distribution of the J&J vaccine drive its inequitable distribution to” hard-hit, marginalized, and medically underserved communities.” (thanx! to XJ/LA)

January 30, 2021


 [JM1]

POST 121. January 30, 2021. CORONVIRUS. Will our communities become stratified by which vaccine is distributed? 95%ters v. 72%ters? Will the easier distribution of the J&J vaccine drive its use in ”hard-hit, marginalized, and medically underserved communities.” (thanx! to XJ/LA)

“On January 15, President Biden and his administration unveiled the outline for a national COVID-19 vaccination strategy, which seeks to address challenges faced by local governments in distributing the vaccine. This five-part plan outlines key actions that the Biden Administration will work to take at the federal level to aid the efficient and equitable vaccination of U.S. residents. Such actions include: Increasing the number of vaccinations by encouraging states to open vaccine availability to other priority groups and ensuring an equitable distribution by targeting resources to hard-hit, marginalized, and medically underserved communities.” (A)

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“So once January 20th comes and you (Dr. Marcella Nunez-Smith). become chair of President Biden’s COVID-19 equity task force, what specifically will you be focusing on? What will your job entail?

One of the priorities is getting from vaccines to vaccination, and having a strategy where everyone in our country who wants a vaccine can get one, with equitable and timely access. That’s going to be a really high priority for us in the first 100 days. We need a whole-of-government approach to this [pandemic], and we have to prioritize both our response and our recovery, with things like PPE, testing, and vaccines.” (B)

Johnson & Johnson’s Covid-19 single-shot vaccine was shown to be 66% effective in preventing moderate and severe disease in a global Phase 3 trial, but 85% effective against severe disease, the company announced Friday.

The vaccine was 72% effective against moderate and severe disease in the US, the company said.

It’s a striking difference from vaccines from Pfizer/BioNTech and Moderna, and it may give pause to people uncertain about which vaccine to get or when they can get one. The vaccines already on the market in the US are about 95% effective overall against symptomatic Covid-19, with perhaps even higher efficacy against severe cases…

Dr. Paul Offit, a vaccine expert at the University of Pennsylvania and a member of the FDA’s Vaccines and Related Biological Products Advisory Committee, said that under normal circumstances, there might not be much of a market for a vaccine that is significantly less effective than two others already on the market. But he added that these are not normal times, with a pandemic raging and shortage of vaccines.

Pfizer and Moderna both use genetic technology called messenger RNA, or mRNA technology. Johnson & Johnson uses a weakened common cold virus, known as adenovirus, to carry genetic instructions into the body to prompt an immune response.

“In a better world, we would have abundant quantities of this messenger RNA vaccine, Pfizer and Moderna, and that would be damning for a vaccine that’s clearly less effective. But that said, we have limited quantities of mRNA vaccine,” Offit said.

Offit has been vaccinated, but said if he had not, he would first search out a Pfizer or Moderna vaccine, and then if he couldn’t find one in reasonable period of time, he would take a Johnson & Johnson vaccine if it was available. Offit said getting one brand of vaccine and later on getting a different vaccine should not pose safety issues.

“I would make an effort to get an mRNA vaccine first,” Offit said. “Not being able to get it, and knowing I might not be able to get Pfizer or Moderna for many months, and knowing this virus is still ranging across the country, I would take J&J in the secure knowledge that I could get Pfizer or Moderna later.” (C)

“What are the added benefits of a Johnson & Johnson vaccine on the market?

The Johnson & Johnson vaccine only requires one shot versus the two doses required from other vaccine companies. This means that more people could be vaccinated quicker and with fewer doses.

“An efficacious one-dose, easy to transport vaccine is huge,” tweeted statistician Natalie Dean,

The vaccine also requires cold-storage requirements, making it easier for countries to access and handle the vials.

It can be stored in a refrigerator for up to three months at 36 degrees F to 46 degrees F, the company said in its press release. Pfizer, in comparison, requires a special deep freezer for its vaccine and dry ice when transporting….

“In other words, we could bring the vaccine to the people,” Dr William Schaffner, an infectious disease specialist, told CNN, “rather than bringing the people to the vaccine.”…

Another benefit of Johnson & Johnson’s vaccine? The company has the manufacturing capacity to “create doses in the billions,” Dr Fauci said. “This has important potential and real implications domestically and globally.”

Many experts have reached the consensus, though, that the Johnson & Johnson vaccine at its current point was a good option for people if Pfizer or Moderna’s vaccine were not available.

“We’re going to be learning a lot about these vaccines over the course of the next three to six months,” Dr Osterholm told CNN. “We’ll have to keep sorting this out. Not sorting out to look at safety. Not sorting it to look at whether you should get it or not. Get it. But we’re going to be constantly re-evaluating it. What’s the best way to protect the most people over time? And that may be that you will be getting a booster dose on a routine basis with one or more vaccines. So I know it’s confusing right now, but I think, get your first dose now. Protect as many people as possible.”…

The US federal government has purchased 100 million doses of Johnson & Johnsons vaccine. The company said it would fulfil all of those doses to the United States by June if it were to receive emergency use authorisation.” (D)

to read POSTS 1-120 in chronological order, highlight and click on

Links to POSTS 1-120

CORONAVIRUS TRACKING

Links to POSTS 1-120

Doctor, Did You Wash Your Hands?®

https://doctordidyouwashyourhands.com/

Curated Contemporaneous Case Study Methodology

Jonathan M. Metsch, Dr.P.H.

https://www.mountsinai.org/profiles/jonathan-m-metsch

PART 1. January 21, 2020. CORONAVIRUS. “The Centers for Disease Control and Prevention on Tuesday confirmed the first U.S. case of a deadly new coronavirus that has killed six people in China.”

PART 2. January 29, 2020. CORONAVIRUS. “If it’s not contained shortly, I think we are looking at a pandemic..”….. “With isolated cases of the dangerous new coronavirus cropping up in a number of states, public health officials say it is only a matter of time before the virus appears in New York City.”

PART3. February 3, 2020. “The Wuhan coronavirus spreading from China is now likely to become a pandemic that circles the globe…”..Trump appeared to downplay concerns about the flu-like virus …We’re gonna see what happens, but we did shut it down..” (D)

PART 4. February 9, 2020. Coronavirus. “A study published Friday in JAMA found that 41% of the first 138 patients diagnosed at one hospital in Wuhan, China, were presumed to be infected in that hospital.….

PART 5. February 12, 2020. CORONAVIRUS. “In short, shoe-leather public health and basic medical care—not miracle drugs—are generally what stop outbreaks of emerging infections..”

POST 6. February 18, 2020.  Coronovirus. “Amid assurances that the (ocean liner) Westerdam was disease free, hundreds of people disembarked in Cambodia…” “ One was later found to be infected”…. “Over 1,000… passengers were in…transit home”…. “This could be a turning point””

PART 7. February 20, 2020. CORONAVIRUS. With SARS preparedness underway in NJ LibertyHealth/ Jersey City Medical Center, where I was President, proposed that our 100 bed community hospital with all single-bedded rooms, be immediately transformed into an EMERGENCY SARS ISOLATION Hospital.

PART 8. February 24, 2020. CORONAVIRUS. “…every country’s top priority should be to protect its health care workers. This is partly to ensure that hospitals themselves do not become sites where the coronavirus is spread more than it is contained.”

PART 9. February 27, 2020. CORONAVIRUS. Responding to a question about the likelihood of a U.S. outbreak, President Trump said, “I don’t think it’s inevitable…”It probably will. It possibly will,” he continued. “It could be at a very small level, or it could be at a larger level.”

Part 10. March 1, 2020. CORONAVIRUS. Stop Surprise Medical Bills for Coronavirus care. (&) Lessons Learned (or not) In California and Washington State from community acquired cases.

PART 11. March 5, 2020.  CORONAVIRUS. “Gov. Andrew Cuomo… would require employers to pay workers and protect their jobs if they are quarantined because of the coronavirus.”

Part 12. March 10, 2020. CORONAVIRUS. “Tom Bossert, Donald Trump’s former homeland security advisor…(said) that due to the coronavirus outbreak, “We are 10 days from the hospitals getting creamed.”

Part 13.. March 14, 2020. CORONAVIRUS. “If I’m buying real estate in New York, I’ll listen to the President….If I’m asking about infectious diseases, I’m going to listen to Tony Fauci,”

PART 14. March 17, 2020. CORONAVIRUS. “ “Most physicians have never seen this level of angst and anxiety in their careers”…. One said “I am sort of a pariah in my family.”

PART 15. March 22, 2020. CORONAVIRUS. “…Crimson Contagion” and imagining an influenza pandemic, was simulated by the Trump administration….in a series of exercises that ran from last January to August.

PART 16. March 27, 2020. CORONAVIRUS. I am not a clinician or a medical ethicist but articles on Coronavirus patient triage started me Googling………to learn about FUTILE TREATMENT

PART 17. April 2, 2020. CORONAVIRUS. Florida allows churches to continue holding services. Gun stores deemed “essential.”  “New York’s private and public hospitals unite to manage patient load and share resources.

PART 18. April 9, 2020. CORONAVIRUS. “The federal government’s emergency stockpile of personal protective equipment (PPE) is depleted, and states will not be receiving any more shipments, administration staff told a House panel.

PART 19. April 13, 2020 CORONOAVIRUS. “…overlooked in the United States’ halting mobilization against the novel coronavirus: the personal aides, hospice attendants, nurses and occupational or physical therapists who deliver medical or support services to patients in their homes.”

PART 20. April 20, 2020. CORONAVIRUS. “…nothing is mentioned in the “Opening Up America Again” plan about how states should handle a resurgence.”

PART 21. April 23, 2020. CORONAVIRUS. “We need to ask, are we using ventilators in a way that makes sense for other diseases but not this one?”

POST 22. April 29, 2020. CORONAVIRUS. ..the “ACS released a list of 10 issues that should be addressed before a healthcare organization resumes elective surgeries[JM1] ….”

POST 23. May 3, 2020. CORONAVIRUS. … what Dr. Fauci really wants,…”is just to go to a baseball game. That will have to wait. The level of testing for the virus is not adequate enough to allow for such mass gatherings.’ (K)

POST 24. May 7, 2020. CORONAVIRUS. Former New Jersey governor Chris Christie said: “there are going to be deaths no matter what”… but that people needed to get back to work.

POST 25. May 10, 2020, CORONAVIRUS. “It is scary to go to work,” said Kevin Hassett, a top economic adviser to the president. “I think that I’d be a lot safer if I was sitting at home than I would be going to the West Wing.”

POST 26. May 14, 2020. CORONAVIRUS, “Deep cleaning is not a scientific concept”….”there is no universal protocol for a “deep clean” to eradicate the coronavirus”

POST 27. May 19, 2020. CORONAVIRUS. “Hospital…executives…are taking pay cuts…to help offset the financial fallout from COVID-19.” As “front line” layoffs and furloughs accelerate…

POST 28. May 23, 2020. CORONAVIRUS. ““You’ve got to be kidding me,”..”How could the CDC make that mistake? This is a mess.” CDC conflates viral and antibody tests numbers.

PART 29. May 22, 2020. CORONAVIRUS. “The economy did not close down. It closed down for people who, frankly, had the luxury of staying home,” (Governor Cuomo). But not so for frontline workers!

POST 30. June 3,202. CORONAVIRUS. “The wave of mass protests across the United States will almost certainly set off new chains of infection for the novel coronavirus, experts say….

POST 31. June 9, 2020. CORONAVIRUS. “I think we had an unintended consequence: I think we made people afraid to come back to the hospital,”

Post 32. June 16, 2020. CORONAVIRUS. Could the Trump administration be pursuing herd immunity by “inaction”?  “ If Fauci didn’t exist, we’d have to invent him.”

POST 33. June 21, 2002. CORONAVIRUS….. Smashing (lowering the daily number of cases) v. flattening the curve (maintaining a plateau)

POST 34. June 26, 2020. CORONAVIRUS. CDC Director Redfield… “the number of coronavirus infections…could be 10 times higher than the confirmed case count — a total of more than 20 million.” As Florida, Texas and Arizona become eipicenters!

POST 35. June 29, 2020. CORONAVIRUS. Pence: “We slowed the spread. We flattened the curve. We saved lives..”  While Dr. Fauci “warned that outbreaks in the South and West could engulf the country…”

POST 36. July 2, 2020. CORONAVIRUS. “There’s just a handful of interventions proven to curb the spread of the coronavirus. One of them is contact tracing, and “it’s not going well,” (Dr. Anthony Fauci)..

POST 37. June 8, 2020. CORONAVIRUS. When “crews arrive at a hospital with a patient suspected of having COVID-19, the hospital may have a physical bed open for them, but not enough nurses or doctors to staff it.”

POST 38. July 15, 2020. CORONAVIRUS. Some Lessons Learned, or not. AdventHealth CEO Terry Shaw: I wouldn’t hesitate to go to Disney as a healthcare CEO — based on the fact that they’re working extremely hard to keep people safe,” (M)

POST 39. July, 23,2020. CORONAVIRUS. A Tale of Two Cities. Seattle becomes New York (rolls back reopening) while New York becomes Seattle (moves to partial phase 4 reopening)

POST 40. July 27, 2020. CORONAVIRUS.” One canon of medical practice is that you order a test only if you can act on the result. And with a turnaround time of a week or two, you cannot. What we have now is often not testing — it’s testing theater.”

POST 41. August 2, 2020. CORONAVIRUS. “Whenever a vaccine for the coronavirus becomes available, one thing is virtually certain: There won’t be enough to go around. That means there will be rationing.”

POST 42. August 11, 2020. CORONAVIRUS. “I think that if future historians look back on this period, what they will see is a tragedy of denial….

POST 43. August 22, 2020. CORONAVIRUS.”  “we’ve achieved something great as a nation. We’ve created an unyielding market for FAUCI BOBBLEHEADS”!! (W)

POST 44.  September 1, 2020. CORONAVIRUS. “The CDC…modified its coronavirus testing guidelines…to exclude people who do not have symptoms of Covid-19.” (While Dr. Fauci was undergoing surgery.) A White House official said: “Everybody is going to catch this thing eventually..”

POST 45. September 9, 2020. CORONAVIRUS.  Trump on Fauci. ‘You inherit a lot of people, and you have some you love, some you don’t. I like him. I don’t agree with him that often but I like him.’

POST 46.  September 17, 2020. CORONAVIRUS. “Bill Gates used to think of the US Food and Drug Administration as the world’s premier public-health authority. Not anymore. And he doesn’t trust the Centers for Disease Control and Protection either….”

POST 47. September 24, 2020. CORONAVIRUS. “Perry N. Halkitis, dean of the School of Public Health at Rutgers University…called New York City’s 35 percent rate for eliciting contacts “very bad.” “For each person, you should be in touch with 75 percent of their contacts within a day,” he said”

POST 48. October 1, 2020.   “…you can actually control the outbreak if you do the nonpharmaceutical interventions (social distancing and masks). In the United States we haven’t done them. We haven’t adhered to them; we’ve played with them.” (A)

POST 49. October 4, 2020. CORONAVIRUS. RAPID RESPONSE. “The possibility that the president and his White House entourage were traveling superspreaders is a nightmare scenario for officials in Minnesota, Ohio, New Jersey and Pennsylvania…”

POST 50. October 6, 2020. CORONAVIRUS. Monday October 5th will go down as one of the most fraught chapters in the history of American public Health (and national security).

POST 51. October 12, 2020. Rather than a hodge-podge of Emergency Use Authorizations, off-label “experimentation”, right-to-try arguments, and “politicized” compassionate use approvals maybe we need to designate REGIONAL EMERGING VIRUSES REFERRAL CENTERS (REVRCs).

POST 52. October 18, 2020.  ZIKA/ EBOLA/ CANDIDA AURIS/ SEVERE FLU/ Tracking. “… if there was a severe flu pandemic, more than 33 million people could be killed across the world in 250 days… Boy, do we not have our act together.” —”- Bill Gates. July 1, 2018

POST 53. October 20, 2020. CORONAVIRUS. “a…“herd-immunity strategy” is a contradiction in terms, in that herd immunity is the absence of a strategy.”

POST 54. October 22, 2020. CORONAVIRUS. POST 54A. New Jersey’s Coronavirus response, led by Governor Murphy and Commissioner of Health Persichilli started with accelerated A+ traditional, evidence-based Public Health practices, developed over years of experience with seasonal flu, swine flu, Zika, and Ebola.

POST 55. October 26, 2020. CORONAVIRUS. The Testing Conundrum: “ It’s thus very possible to be antigen negative but P.C.R. positive, while still harboring the virus in the body..”

Post 56. October 30, 2020. CORONAVIRUS. “Trump’s now back in charge. It’s not the doctors.”

POST 57. November 3, 2020. CORONAVIRUS. Dr. Deborah Birx: the US is entering its “most deadly phase” yet, one that requires “much more aggressive action,”

POST 58. November 4, 2020. CORONAVIRUS. “…the president has largely shuttered the White House Coronavirus Task Force and doubled down on anti-science language…”

POST 59. November 5, 2020. Coronavirus. “The United States on Wednesday recorded over 100,000 new coronavirus cases in a single day for the first time since the pandemic began..

POST 60. November 7, 2020. “White House chief of staff Mark Meadows has tested positive for the coronavirus….” (A)

POST 61. November 7, 2020. CORONAVIRUS. “Joe Biden’s top priority entering the White House is fighting both the immediate coronavirus crisis and its complex long-term aftermath…” “Here are the key ways he plans to get US coronavirus cases under control.”

POST 62. November 8, 2020. CORONAVIRUS. “The United States reported its 10 millionth coronavirus case on Sunday, with the latest million added in just 10 days,…”

POST 63. November 9, 2020. CORONAVIRUS. “New York City-based Mount Sinai Health System has opened a center to help patients recovering from COVID-19 and to study the long-term impact of the disease….”

POST 64. November 10, 2020. CORONAVIRUS. “It works! Scientists have greeted with cautious optimism a press release declaring positive interim results from a coronavirus vaccine phase III trial — the first to report on the final round of human testing.”

POST 65. November 11, 2020. CORONAVIRUS, “The Centers for Disease Control and Prevention took a stronger stance in favor of masks on Tuesday, emphasizing that they protect the people wearing them, rather than just those around them…

POST 66. November.12, 2020. CORONAVIRUS.”… as the country enters what may be the most intense stage of the pandemic yet, the Trump administration remains largely disengaged.”… “President-elect Biden has formed a special transition team dedicated to coordinating the coronavirus response across the government…”

POST 67. November 13, 2020. CORONAVIRUS. “When all other options are exhausted, the CDC website says, workers who are suspected or confirmed to have COVID-19 (and “who are well enough to work”) can care for patients who are not severely immunocompromised — first for those who are also confirmed to have COVID-19, then those with suspected cases.”

POST 68. November 14, 2020. CORONAVIRUS. The CDC “now is hewing more closely to scientific evidence, often contradicting the positions of the Trump administration.”..” “A passenger aboard the first cruise ship to set sail in the Caribbean since the start of the pandemic has tested positive for coronavirus..”

POST 69. November 15, 2020. CORONAVIRUS. “Colorado Gov. Jared Polis will issue a new executive order outlining steps hospitals will need to take to ready themselves for a surge in COVID-19 hospitalizations and directing the hospitals to finalize plans for converting beds into ICU beds, adding staffing and scaling back on or eliminating elective procedures….

POST 70. November 16, 2020. CORONAVIRUS. “White House coronavirus task force member Dr. Atlas criticized Michigan’s new Covid-19 restrictions..urging people to “rise up” against the new public health measures.

POST 71. November 17, 2020. CORONAVIRUS. ”Hospitals overrun as U.S. reports 1 million new coronavirus cases in a week.” “But in Florida, where the number of coronavirus infections remains the third-highest in the nation, bars and schools remain open and restaurants continue to operate at full capacity.”

POST 72. November 18, 2020. CORONAVIRUS. “The Health and Human Services Department will not work with President-elect Joe Biden’s (PANDEMIC) team until the General Services Administration makes a determination that he won the election,….”

POST 73. November 19, 2020. CORONAVIRUS. “…officials at the CDC…urged Americans to avoid travel for Thanksgiving and to celebrate only with members of their immediate households…” When will I trust a vaccine? to the last question I always answer: When I see Tony Fauci take one….”

POST 74. November 20, 2020. CORONAVIRUS. Pfizer…submitted to the FDA for emergency use authorization for their coronavirus vaccine candidate. —FDA issued an EUA for the drug baricitinib, in combination with remdesivir, as WHO says remdesivir doesn’t do much of anything.

POST 75. November 21, 2020. CORONAVIRUS. “The president and CEO of one of the nation’s largest non-profit health systems says he won’t be wearing a mask at work because he’s recovered from COVID-19, and doing so would only be a “symbolic gesture” because he considers himself immune from the virus….

POST 76. November 23, 2020. CORONAVIRUS. “No battle plan survives contact with the enemy.” Ventilators..”just keep people alive while the people caring for them can figure out what’s wrong and fix the problem. And at the moment, we just don’t have enough of those people.”

POST 77. November 26, 2020. CORONAVIRUS. Pope Francis: “When I got really sick at the age of 21, I had my first experience of limit, of pain and loneliness.”.. “….Aug. 13, 1957. I got taken to a hospital…”….” I remember especially two nurses from this time.”…” They fought for me to the end, until my eventual recovery.”

POST 78. November 27, 2020. CORONAVIRUS. “Kelby Krabbenhoft is no longer president and CEO of Sioux Falls, S.D.-based Sanford Health.” “…for not wearing a face covering… “ because “He considered himself immune from the virus.”

POST 79. November 28, 2020. CORONAVIRUS. Mayo Clinic. “”Our surge plan expands into the garage…”..””Not where I’d want to put my grandfather or my grandmother,” … though it “may have to happen.”

POST 80. November 29, 2020. CORONAVIRUS. Op-Ed in the Jersey Journal. Do you know which hospital is right for you if you have coronavirus? | Opinion

POST 81. December 1, 2020. CORONAVIRUS. “Dr. Atlas, … who espoused controversial theories and rankled government scientists while advising President Trump on the coronavirus pandemic, resigned…”

POST 82. December 3, 2020. CORONAVIRIUS. The NBA jumped to the front of the line for Coronavirus testing….while front line nurses often are still waiting. Who will similarly “hijack” the vaccine?

POST 83. December 4, 2020. CORONAVIRUS. “California Gov. Gavin Newsom says he will impose a new, regional stay-at-home order for areas where capacity at intensive care units falls below 15%.”… East Tennessee –“This is the first time the health care capability benchmark has been in the red..”

POST 84. December 6, 2020. CPRONAVIRUS. “ More than 100,000 Americans are in the hospital with COVID-19…” “We’re seeing C.D.C. …awaken from (its) politics-induced coma…”…Dr. Fauci “to be a chief medical adviser in Biden’s incoming administration..”.. “Trump administration leaves states to grapple with how to distribute scarce vaccines..”

POST 85. December 7, 2020. CORONAVIRUS. “…Florida, Gov. DeSantis’ administration engaged in a pattern of spin and concealment that misled the public on the gravest health threat the state has ever faced..”.. “NY Gov. Cuomo said…the state will implement a barrage of new emergency actions..”… Rhode Island and Massachusetts open field hospitals… “Biden Names Health Team to Fight Pandemic”

POST 86. December 9, 2020. If this analysis seems a bit incomprehensible it is because “free Coronavirus test” is often an oxymoron! with charges ranging from as little as $23 to as much as $2,315… Laws (like for free Coronavirus tests) are Like Sausages. Better Not to See Them Being Made. (Please allow about 20 seconds for the text to download. Thanx!)

POST 87. December 10, 2020. CORONAVIRUS. “…Rudolph W. Giuliani, the latest member of President Trump’s inner circle to contract Covid-19, has acknowledged that he received at least two of the same drugs the president received. He even conceded that his “celebrity” status had given him access to care that others did not have.”

POST 88. December 11, 2020. CORONAVIRUS. “As COVID-19 cases surge, the federal government is releasing data about hospital capacity at facilities around the country….”The new data paints the picture of how a specific hospital is experiencing the pandemic,”…

PART 89. December 12, 2020. CORONAVIRUS. THE VACCINE!!! “Now this is not the end. It is not even the beginning of the end. But it is, perhaps, the end of the beginning.” Winston Churchill

POST 90. December 14, 2020. CORONAVIRUS. “…the first doses of a Covid-19 vaccine have been given to the American public..”…” Each person who receives a vaccine needs two doses, and it’s up to states to allocate their share of vaccines.”

POST 91. December 15, 2020. CORONAVIRUS. “UPMC will first give (vaccination) priority to those in critical jobs. That includes a range of people working in critical units, from workers cleaning the emergency room and registering patients to doctors and nurses.. “Finally, if needed, UPMC will use a lottery to select who will be scheduled first.”

POST 92. December 17, 2020. CORONAVIRUS. “..each state — and each hospital system — has come up with its own (vaccination) plan and priorities. The result has been a sometimes confusing constellation of rules and groupings that has left health care workers wondering where they stand.” (Trump appointee July 4th email “…we need to establish herd, and it only comes about allowing the non-high risk groups expose themselves to the virus. PERIOD,”)

POST 93. December 19, 2020. CORONAVIRUS.  On NPR Congresswoman Shalala (D-Florida) said she wouldn’t jump the vaccination line in Miami; then added she would get vaccinated in Washington this week. This, even though Congress has failed to pass “essential” Coronavirus legislation. So who are our “essential” workers?

POST 94. December 21, 2020. CORONAVIRUS. “A doctor at an L.A. County public hospital said the number of COVID-19 patients is “increasing exponentially, without an end in sight.”.. “I haven’t done ICU medicine since I was a resident — you don’t want me adjusting your ventilator,” he said. “That’s the challenge, actually — it isn’t so much space, it’s staff…”

POST 95. December 23, 2020. “The Murphy administration may step in to force (New Jersey) hospitals to report COVID-19 outbreaks among staff.”

POST 96. December 26, 2020. CORONAVIRUS. “Achieving herd immunity against the coronavirus could require as much as 90 percent of the population to be vaccinated, Anthony Fauci…”…”..he hesitated to state a number as high as 90% weeks ago because many Americans still seemed skeptical about vaccine….”

POST 97. December 27, 2020. “A new variant of the coronavirus that has been spreading through the UK and other countries has not yet been detected in the United States..”.. . But if new-wave medicines like antivirals and antibody therapy contributed to the development of viral variants, it will be “a reminder for all the medical community that we need to use these treatment options carefully.”

POST 98. December 28, 2020. CORONAVIRUS. “Governor Andrew Cuomo announced new penalties in order to rein in possible vaccination fraud…

POST 99. December 29, 2020. CORONAVIRUS. “ICUs are being overwhelmed across many parts of California. Statewide aggregate ICU availability has been at 0% since Christmas Eve…. a surge on top of a surge on top of a surge.”… “hospitals are getting close to the point where they would begin putting COVID-positive patients under the care of COVID-positive staff who are asymptomatic.”

POST 100. December 29, 2020. CORONAVIRUS. Front line hospital workers – in the ER, ICUs, EMS, acute medical care, behavioral health – are amongst the most courageous, heroic and dedicated colleagues you will ever meet.

POST 101. December 30, 2020.CORONAVIRUS. Is there a point where the increasing Coronavirus trajectory so far exceeds the slow growth of the vaccination rate that reaching herd immunity through vaccinations becomes less likely?

POST 102. January 2, 2020. CORONAVIRUS. “We’ve taken the people with the least amount of resources and capacity and asked them to do the hardest part of the vaccination — which is actually getting the vaccines administered into people’s arms,” said Dr. Ashish Jha, the dean of Brown University’s School of Public Health. “Ultimately, the buck seems to stop with no one,”…

POST 103. January 4, 2021. CORONAVIRUS. Dr. Fauci said “that the United States would not follow Britain’s lead in front-loading first vaccine injections, potentially delaying the administration of second doses…Dr. Moore – ”British officials “seem to have abandoned science completely now and are just trying to guess their way out of a mess.”

POST 104. January 6, 2021. CORONAVIRUS. “Paramedics in Southern California are being told to conserve oxygen and not to bring patients to the hospital who have little chance of survival…”

POST 105. January 8, 2021. CORONAVIRUS. POST 105. January 8, 2021. CORONAVIRUS. “Facing a shortage of vaccinators, the Association of Immunization Managers… recommends relaxing regulation or adjusting licensing requirements. At least two states, Massachusetts and New York, have changed their laws in recent weeks to expand those who are eligible to give shots.”

POST 106. January 9, 2021. CORONAVIRUS. The riots at the Capitol could have been a superspreader event. “From what I saw… you had a large congregation of individuals who were in close contact for an extended period of time and almost universally unmasked…. many coming and going on buses as well, also unmasked, and hanging out in hotel lobbies.”

POST 107. January 8, 2021. CORONAVIRUS. “Our job is to make sure the vaccine isn’t politicized the way masks were politicized,” Rep. Alexandria Ocasio-Cortez, D-N.Y., said after getting her vaccine.   South Carolina Rep.-elect Nancy Mace, a Republican, wrote that “Congress shouldn’t be putting themselves first in line for the COVID-19 vaccination when the average American can’t get it.”

POST 108. January 9, 2021. CORONAVIRUS. (vaccination)”Line-cutters will be named and shamed. It’s inevitable, as will be the congressional hearings and front-page investigative stories ferreting out who saved their own skin at the expense of others.” 

POST 109.January 9, 2021. CORONAVIRUS. “President-elect Joe Biden will aim to release nearly every available dose of the coronavirus vaccine when he takes office, a break with the Trump administration’s strategy of holding back half of US vaccine production to ensure second doses are available.

POST 110. January 13, 2021. CORONAVIRUS. ““The (federal) government is changing the way it allocates Covid vaccine doses, now basing it on how quickly states can administer shots and the size of their elderly population.”… “New York State sent a letter to hospitals saying if they don’t use their vaccine allocations by the end of this week, they won’t receive any further allocations.”

POST 111. January 14, 2021. CORONAVIRUS. “Visitors from Toronto to New York to Buenos Aires have long flocked to Florida for sun, surf and shopping. Now they are coming for the Covid-19 vaccine….

POST 112. January 14, 2021. CORONAVIRUS. CHINA – “Eleven million people are under lockdown in Hebei province after a new cluster of coronavirus infections.

PART 113. January 17, 2021. CORONAVIRUS. The Next President Actually Has a Covid Plan… New York City and other places in the state expect to exhaust their supply of doses as early as next week… Charles Barkley said during the “NBA on TNT” broadcast that pro athletes should get the first round of the vaccine…..

POST 114. January 18, 2021. CORONAVIRUS. “When government programs that have been unattended, underfunded and bogged down by red tape suddenly have to meet a huge demand in a crisis, they can’t cope and people suffer….”

POST 115. January 21, 2020. CORONAVIRUS. A year ago today an unnumbered POST was headlined “The Centers for Disease Control and Prevention on Tuesday confirmed the first U.S. case of a deadly new coronavirus that has killed six people in China.” The CORONAVIRUS CONTENT TRACKING PROJECT started with HISTORIOGRAPHY and over time moved to LESSONS LEARNED, RAPID RESPONSE, and THE VACCINATION PROGRAM. Now 115 POSTS later – the BIDEN CORONAVIRUS PLAN.

POST 116. January 22, 2021. President Biden – “We’re entering what may be the toughest and deadliest period of the virus. We must set aside politics and finally face this pandemic as one nation.”

POST 117. January 23, 2021. CORONAVIRUS. 1.Dr. Fauci:“The idea that you can get up here….”and.. let the science speak”… “It is somewhat of a liberating feeling.” 2.updated CDC guidance:”.. providers could give the second dose up to six weeks after the first dose..” 3.Dr. Fauci: people would be “taking a chance” if they follow the CDC’s updated guidance.

POST 118. January 24, 2021. CORONAVIRUS. “Unfortunately, we’ve let this virus spread extensively and are launching the vaccination campaign at the height of the threat,” Dr. Meyers said. “The more the virus spreads before the vaccine reaches people, the fewer deaths we can prevent with the vaccine.”

POST 119. January 27, 2010. CORONAVIRUS. Amazon is offering its help to President Joe Biden with the rollout of COVID-19 vaccines. Washington’s governor, Jay Inslee, included the help of companies like Starbucks, Costco and Microsoft in a plan to vaccinate 45,000 residents a day.

POST 120. January 28, 2021. CORONAVIRUS. “The fact that four vaccines backed by the federal government seem to be less effective against the (South African) B.1.351 variant has unsettled federal officials and vaccine experts alike. Facing this uncertainty, many researchers said it was imperative to get as many people vaccinated as possible — quickly. Lowering the rate of infection could thwart the contagious variants while they are still rare, and prevent other viruses from gaining new mutations that could cause more trouble.”

January 29, 2021


 [JM1]

POST 120. January 28, 2021. CORONAVIRUS. “The fact that four vaccines backed by the federal government seem to be less effective against the (South African) B.1.351 variant has unsettled federal officials and vaccine experts alike. Facing this uncertainty, many researchers said it was imperative to get as many people vaccinated as possible — quickly. Lowering the rate of infection could thwart the contagious variants while they are still rare, and prevent other viruses from gaining new mutations that could cause more trouble.”

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“A new and highly contagious coronavirus variant first identified in South Africa has been found in the United States for the first time, with two cases diagnosed in South Carolina, state health officials said Thursday. The two cases don’t appear to be connected, nor do the people have a history of recent travel, the South Carolina Department of Health and Environmental Control said…

Viruses are constantly mutating, with coronavirus variants circulating around the globe, but scientists are primarily concerned with the recent emergence of three of them. Other variants first detected in the United Kingdom and Brazil have also been confirmed in the U.S.  Researchers believe these three variants may spread more easily, and predicted it was only a matter of time before they appeared here.

“At this time, we have no evidence that infections by this variant cause more severe disease,” the U.S. Centers for Disease Control and Prevention said in a statement. “Like the UK and Brazilian variants, preliminary data suggests this variant may spread more easily and quickly than other variants.”

Also, scientists last week reported preliminary but troubling signs that some of the recent mutations may modestly reduce the strength of two current vaccines, although they stressed that the shots still protect against the disease. And there are signs that some of the new mutations may undermine tests for the virus and reduce the effectiveness of certain treatments…

Some tests suggest the South African and Brazilian variants may be less susceptible to antibody drugs or treatment with antibody-rich blood plasma from COVID-19 survivors, both of which help people fight off the virus.” (A)

“Several coronavirus variants have emerged in recent weeks that spread from person to person more easily than the dominant strain that’s driven the Covid-19 pandemic thus far. The variants were first identified in the United Kingdom, South Africa and Brazil, Andrew Joseph reports for STAT. New research suggests yet another variant has emerged in California as well.

The presence of coronavirus variants raises several questions about how the pandemic will play out in the coming months. Even countries that have taken strict precautions to prevent the virus’ spread, like Denmark, have seen a rise in variant infections.

Currently accessible Covid-19 vaccines still appear to protect people against the emerging variants, and officials emphasize the importance of following through on vaccine distribution plans, reports National Geographic’s Michael Greshko.

“There is a very slight, modest diminution in the efficacy of a vaccine against it, but there’s enough cushion with the vaccines that we have that we still consider them to be effective,” Anthony Fauci, the nation’s leading infectious diseases official, said Monday on the “Today” show.

The virus, called SARS-CoV-2, has a genetic code written with RNA instead of DNA. Sometimes, as the virus is making copies of itself, it makes a mistake when re-writing its RNA. Coronaviruses are usually able to catch and correct their mistakes, but sometimes a genetic typo makes its way into a new generation of viruses.

Sometimes those typos have no effect on the virus, and sometimes they actually hurt the virus. But the recently-identified variants, through some combination of several typos, got an advantage: increased transmission….

In the U.S., the CDC warned that the U.K. variant of the coronavirus may become the most common form of the virus by March, Erin Garcia de Jesus reports for Science News. It has already been identified in 22 states, per CNN, and it is particularly common in Florida and California.

The variant is about 30 to 70 percent more contagious than versions of the virus that have circulated for the past year, per the Washington Post, and early data suggests it may be more deadly as well…”  (B)

“Goldstein has a simpler explanation, one that’s beginning to get more traction in the scientific community. The convergent evolution of wilier versions of the virus might just be a consequence of so many poorly managed government pandemic responses, which didn’t marshal sufficient resources or inspire the kind of collective action required to not just crush the initial curve, but keep it crushed. “The fact that we lost control in so many places in the fall allowed for the ballooning of this incredibly huge viral population size,” says Goldstein. That created the opportunity for that many more mutations to happen, and in some places, the right circumstances for some particularly insidious ones to get selected.

Hanage put it this way to reporters last week: “The strategy here and elsewhere has been to try and control the level of transmission that doesn’t require very severe restrictions, but also doesn’t allow the virus to go exponential and overload health care systems.” But the problem with that approach is that it still gives the virus plenty of opportunities to mutate, and in so doing, change its behavior. If those changes make it spread faster or give it an edge against treatments and vaccines, that balancing act falls apart. “It tips you from a point where you’re capable of dealing with it to a point where you’re not,” he continued…

Scientists may never get a clear answer to exactly where and under what conditions these new variants emerged. But de Oliveira isn’t so sure it matters. “The one thing we know for sure is that if you keep the virus circulating long enough, it will develop escape mutations,” he says.

The much more pressing question, then, is to what degree will such mutations affect efforts to vaccinate our way out of the pandemic?..

In a statement, Moderna CEO Stéphane Bancel said that he is confident the company’s vaccine should still be protective against the newly detected variants, but that “it is imperative to be proactive as the virus evolves.” To that end, Moderna’s scientists are retooling the company’s mRNA sequence to more closely mimic the most significant mutations and plan to test it as an additional booster shot in clinical studies later this year.

“We shouldn’t panic yet, but we should be careful. This is a warning,” says Hatziioannou. “If the virus continues to accumulate mutations in its spike protein, we run the risk of the efficacy of vaccines diminishing further.”..

With these new variants showing signs of being better at spreading and eluding both natural immune defenses and treatments like monoclonal antibodies and convalescent serum, the race is on to vaccinate as many people as possible in the shortest time frame. At least in the US, the last mile challenges with getting ultra-cold, two-shot vaccines into people’s arms are proving so problematic that the Biden administration has proposed creating 100 new mass vaccination sites across the country.

That’s good. But scientists like Hanage are still worried that if governments and societies don’t do enough to slow the speed of infections soon, more dangerous mutations will almost certainly emerge. “The fact that it’s happened three times already means we can expect it to continue happening,” he said during last week’s press briefing.” (C)

“Experts still don’t know what metrics, such as antibody levels in the blood, signal if a person is protected from the coronavirus. That makes it hard to tell from experiments done with lab-grown cells whether low levels of neutralizing antibodies are enough to stop an infection in a person or protect them from developing severe COVID-19, says Stuart Ray, a virologist and infectious disease physician at Johns Hopkins University School of Medicine.

While the preliminary results hint at some trouble for vaccines, there’s not yet enough evidence to push scientists to begin giving people updated shots. For that, “I think we’d need to see evidence of reinfections in people who had well demonstrated immune responses” to the coronavirus, Ray says.

If it did come to that point, some types of vaccines could be easier to update than others. A new version of mRNA vaccines like Pfizer’s and Moderna’s could be made in the lab in a few days, says John Mascola, director of the Dale and Betty Bumpers Vaccine Research Center at NIAID. Moderna announced January 25 that the company plans to run clinical trials to test whether vaccinated people could get a third dose of its vaccine. Moderna is also planning to test a booster shot that uses a protein from the coronavirus variant in South Africa. Pfizer has said that the company is laying the groundwork to tweak its vaccine.

Other vaccines, like AstraZeneca’s or Johnson & Johnson’s, need to be produced in lab-grown cells, which could take a few weeks (SN: 11/23/20). Companies would then need to ramp up manufacturing for millions of doses, which takes time.

But one complication is how regulatory agencies like the FDA might want to test updated vaccines tweaked to target new coronavirus variants. So far, that is unclear. If experts learn what immune system signals correlate with immunity in ongoing clinical trials, new vaccines might be tested in tens or hundreds of people — as agencies already do for updated influenza vaccines — rather than tens of thousands. But for now, Mascola says, “it is uncharted territory.” “ (D)

“Novavax, a little-known company supported by the U.S. federal government’s Operation Warp Speed, said for the first time on Thursday that its Covid-19 vaccine offered robust protection against the virus. But it also found that the vaccine is not as effective against the fast-spreading variant first discovered in South Africa, another setback in the global race to end a pandemic that has already killed more than 2.1 million people.

That could be a problem for the United States, which hours earlier reported its first known cases of the contagious variant in two unrelated people in South Carolina. And it came just days after Moderna and Pfizer said that their vaccines were also less effective against the same variant.

Novavax, which makes one of six vaccine candidates supported by Operation Warp Speed last summer, has been running trials in Britain, South Africa, the United States and Mexico. It said Thursday that an early analysis of its 15,000-person trial in Britain revealed that the two-dose vaccine had an efficacy rate of nearly 90 percent there. But in a small trial in South Africa, the efficacy rate dropped to just under 50 percent.

Almost all the cases that scientists have analyzed there so far were caused by the variant, known as B.1.351. The data also showed that many trial participants were infected with the variant even after they had already had Covid.” (E)

“Johnson & Johnson announced on Friday that its one-dose coronavirus vaccine provided strong protection against Covid-19, potentially offering the United States a third powerful tool in a desperate race against a worldwide rise in virus mutations.

But the results came with a significant cautionary note: The vaccine’s efficacy rate dropped from 72 percent in the United States to 57 percent in South Africa, where a highly contagious variant is driving most cases. Studies suggest that this variant also blunts the effectiveness of Covid vaccines made by Pfizer-BioNTech, Moderna and Novavax. The variant has spread to at least 31 countries, including the United States, where two cases were documented this week.

Johnson & Johnson said that it planned to apply for emergency authorization of the vaccine from the Food and Drug Administration as soon as next week, putting it on track to receive clearance later in February.

“This is the pandemic vaccine that can make a difference with a single dose,” said Dr. Paul Stoffels, the chief scientific officer of Johnson & Johnson.

While less effective than the Moderna and Pfizer vaccines, Johnson & Johnson’s is still considered a strong vaccine by scientists. Annual flu vaccines, for example, are typically 40 to 60 percent effective.

The company’s announcement comes as the Biden administration is pushing to immunize Americans faster even with a tight vaccine supply. White House officials have been counting on Johnson & Johnson’s vaccine to ease the shortfall. But the company may only have about seven million doses ready when the F.D.A. decides whether to authorize it, according to federal health officials familiar with its production, and about 30 million doses by early April.

The variant from South Africa, known as B.1.351, could make things even worse for the vaccine push. Given the speed at which the variant swept through that country, it is conceivable that by April it could make up a large fraction of infections in the United States. That would undermine the effectiveness of available vaccines.

The fact that four vaccines backed by the federal government seem to be less effective against the B.1.351 variant has unsettled federal officials and vaccine experts alike. Facing this uncertainty, many researchers said it was imperative to get as many people vaccinated as possible — quickly. Lowering the rate of infection could thwart the contagious variants while they are still rare, and prevent other viruses from gaining new mutations that could cause more trouble.” (F)

POST 119. January 27, 2010. CORONAVIRUS. Amazon is offering its help to President Joe Biden with the rollout of COVID-19 vaccines. Washington’s governor, Jay Inslee, included the help of companies like Starbucks, Costco and Microsoft in a plan to vaccinate 45,000 residents a day.

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“Former White House coronavirus task force official Dr. Deborah Birx revealed Sunday that Donald Trump used mysterious graphs during presentations on COVID-19 that she did not create, which provided selective, misleading data.

“I saw the president presenting graphs that I never made,” Birx said in an interview on “Face the Nation” on CBS. “I know that someone — someone out there or someone inside — was creating a parallel set of data and graphics that were shown to the president … You can’t do that,” she added. “You have to use the entire database.”

Trump was mocked for a fistful of charts he brought to an Axios interview last summer, which he had difficulty explaining or understanding…

Birx said there were people in the White House who “definitely” believed that COVID — which has now killed more than 400,000 people in the nation — was a “hoax.” (H)

“So how slow was the rollout under the Trump administration?

First target missed

As of 20 January, the day Mr Biden became president, about 16.5 million vaccines had been administered in the US, according to official statistics….

However, the US fell far short of the target set by the Trump administration to vaccinate 20 million people by the end of 2020….

The daily average for the week before Mr Trump left office was less than 900,000, according to Our World in Data, although there could be a slight lag in recording daily vaccination figures…

There are wide variations across different US states – for example, as of 20 January, Alaska had given out more than 9,000 doses per 100,000 people and Alabama less than 3,000…

Mr Trump focused attention on what he saw as slow delivery by individual states, rather than issues at the federal level.

He tweeted on 29 December: “The Federal Government has distributed the vaccines to the states. Now it is up to the states to administer. Get moving!”

There have been issues around co-ordination and preparedness at state level, but local authorities have put this down to a lack of support from the federal government once the vaccines are distributed….

President Biden’s Chief of Staff, Ron Klain has said a plan to distribute vaccines “out into the community as a whole, did not really exist when we came into the White House”.

Experts say significant logistical problems have arisen as well in administering the vaccines once they have been delivered to states.

As of 20 January, more than 35 million vaccines had been distributed across the US, but less than half of these had been put into people’s arms.

Public health professor at George Washington University, Dr Leana Wen said: “The federal government seemed to have ceded its responsibility at the point the vaccines were given to the states.

“The state and local health departments have been asking for months for additional funding, and have not been given the funding that they need,” she added… (A)

“New Jersey officials have conceded there is a disconnect between the state-run online vaccine registration system and the 200-plus COVID-19 vaccination sites run by local and county governments, health care providers and pharmacies.

The gap turns out to be significant, according to a state list updated Tuesday.

Less than 5% of the coronavirus immunization programs now operating in New Jersey are using the state’s registration system, with the vast majority running their own sign-up process through existing corporate or government websites or newly created portals specific to their location. Only one of the six state-overseen vaccine mega-sites — in Gloucester County — is linked to the New Jersey Vaccine Scheduling System, or NJVSS.

This uncoordinated registration system is frustrating the public as New Jersey residents eager to get vaccinated discover they cannot easily make an appointment through the state portal. Instead, the state scheduling system — which officials said has now pre-registered more than 2 million people — is designed to alert individuals when they are eligible and prompt them to make an appointment at a local vaccine clinic, which usually involves additional calls, emails or a separate sign-up process to secure a spot…

There are now 205 vaccine sites established, according to a DOH list updated Tuesday, although not all are operating at full capacity; nine rely on the NJVSS system.

All are connected to the state’s pre-existing vaccine inventory database, the New Jersey Immunization Information System, or NJIIS, which allows DOH to track their “throughput” and make allocation decisions for the week to come. Doses are shipped directly from federal stockpiles to the immunization sites.

While the state’s updated 190-page vaccine plan, submitted to federal officials in December, notes the importance of carefully tracking all doses — something that fell short during the H1N1 vaccine campaign in 2009 — it provides little detail on the public sign-up process and only mentions the NJVSS system once. Dispensing sites are responsible for everything from set-up to vaccine storage to patient registration, the plan notes, and offers various options for scheduling appointments…

“We are also exploring streamlining registration and scheduling at all of our sites that do not currently participate in NJVSS,” Persichilli said Monday. “Our attempt is to make appointment scheduling easier and one-stop shopping.”..

However, the NJVSS system does not currently have the capacity to schedule appointments for second doses, Persichilli noted Monday…

State officials also did not comment on why the registration system was not designed to handle return visits from the start, but stressed it was currently being updated to accommodate this element. The state’s vaccine plan appears to offer multiple suggestions on how clinics can schedule booster shots — including utilizing NJVSS.”  (B)

“The big reason for the slow vaccine rollout in New Jersey “is the federal program with CVS and Walgreens,” Murphy said. “They basically amassed these doses, they schedule visits to long-term care nursing homes, extended living, and they’re punching under their weight, particularly Walgreens, and that’s where most of the yet to be used doses are.”

New Jersey has a population of approximately 8.882 million people, and has distributed 898,550 vaccines, while only administering 432,220 of them, according to the Centers for Disease Control and Prevention.

“There’s no question we have an enormous supply/demand imbalance, that begins, with all due respect, with the federal government, at least up until today, having dropped the ball – over promising and under delivering,” Murphy said.

New Jersey Gov. Phil Murphy (D) blamed Walgreens and the federal government for the Garden State’s sluggish vaccine rollout during a Wednesday evening interview on CNBC’s “The News with Shepard Smith.”

“The big reason is the federal program with CVS and Walgreens,” Murphy said. “They basically amassed these doses, they schedule visits to long-term care nursing homes, extended living, and they’re punching under their weight, particularly Walgreens, and that’s where most of the yet to be used doses are.”

Murphy suggested to host Shepard Smith that Walgreens “put more bodies on the case” in order to solve the rollout problem.

On Tuesday, Murphy said that New Jersey was effectively equipped to dole out the vaccine, but that all the providers were missing “are the vaccine doses.” New Jersey has a population of approximately 8.882 million people, and has distributed 898,550 vaccines, while only administering 432,220 of them, according to the Centers for Disease Control and Prevention.

Murphy pointed to the Covid vaccine doses under state control and said that they are getting into people’s arms more efficiently.

“You can’t find many doses in hospitals or other distribution points that we control directly, that are going unused,” Murphy said. “We’re getting shots into arms with all of the areas that we can control.”  (E)

“President Joe Biden announced a series of measures on Tuesday aimed at ramping up coronavirus vaccine allocation and distribution, including the purchase of 200 million more vaccine doses and increased distribution to states by millions of doses next week.

With those additional doses, Biden said there would be enough to fully vaccinate 300 million Americans — nearly the entire US population — by the end of summer or early fall.

He described efforts to combat Covid-19 as a “wartime undertaking.”

“We now have a national strategy to beat Covid-19. It’s comprehensive. It’s based on science, not politics. It’s based on truth, not denial, and it is detailed,” he said.

As part of the new efforts announced Tuesday, the US will buy 100 million more doses from Pfizer/BioNTech and 100 million more from Moderna — the two-dose vaccines that have been granted emergency use authorization by the US Food and Drug Administration. Pfizer and Moderna are working to step up production, and Biden said that the additional doses will be available this summer.

The new purchase will increase the planned Covid-19 vaccine supply from 400 million to 600 million, an official told reporters on a call on Tuesday ahead of Biden’s remarks.

The President also took action on Tuesday to increase the weekly vaccine supply to states, tribes and territories — upping the current 8.6 million doses to a minimum of 10 million doses weekly. Additionally, the White House will be providing three week vaccine supply look-ahead reports to states as opposed to one week look-aheads.

Biden’s Covid coordinator, Jeff Zients, informed governors on a call Tuesday afternoon that Covid vaccine allocations for states would increase by around 16% starting next week.

A White House document explaining the move says the Biden administration is committing to maintaining this as the minimum supply level for the next three weeks.

The new efforts come one day after the President said he expects the US will soon be able to vaccinate 1.5 million people a day, which is a notable increase from the administration’s previously stated target of 1 million per day. The President said that the US could surpass that initial target in about three weeks, and said that he thinks anyone who wants a vaccine will be able to get it by this spring.

Biden’s official goal on administering vaccines still remains 100 million shots in his first 100 days in office, multiple White House officials told CNN, after Biden raised the new 1.5 million doses a day aspiration. That initial goal is enough to cover 50 million Americans with vaccines that require two doses.” (C)

“Smarter testing, faster vaccinations and health equity are cornerstones of the 200-page COVID-19 strategy released by US President Joe Biden’s administration on 21 January, as the country surpassed 420,000 deaths due to the coronavirus. The plan pledges to “listen to science” — a shift from the approach of former president Donald Trump, who, at times, politicized scientific evidence and ignored public health recommendations.

Many researchers posted messages on Twitter expressing relief that scientific evidence would play a central role in Biden’s plan. They also celebrated the existence of a coordinated national pandemic strategy, complaining that Trump’s failure to enact one impaired testing, tracing and other responses required to tame the outbreak.

Joe Biden’s COVID plan is taking shape — and researchers approve

“This marks a pretty radical shift,” says J. Stephen Morrison, director of global health policy at the Center for Strategic and International Studies in Washington DC, who compares Biden’s strategy to a wartime national mobilization…

The Biden plan aims to ensure that all Americans can be tested regularly for coronavirus infection by increasing the number of testing sites, and by scaling up the production of rapid tests. Helen Chu, an infectious disease researcher at the University of Washington in Seattle, says more testing will help, but it won’t be enough if the tests don’t reach communities hit hardest by the virus. She says the US government must figure out how to expand home testing for people who can’t get to testing sites because of work, childcare duties or a lack of transportation.

Increasing the United States’ surveillance for new, potentially dangerous, variants of SARS-CoV-2 is also part of the Biden administration’s plan. But Chu wants to see a systematic strategy for sequencing the genomes of coronaviruses across the country, as opposed to researchers conducting studies on samples they happen to obtain through fragmented projects. “Right now, surveillance is being led by academic research labs in a piecemeal way,” she says, “and not at the coordinated high-throughput level that you need to identify and act on new variants quickly.”

Biden’s strategy also calls for a better online dashboard for tracking the prevalence of the virus in cities and towns across the United States, so that people and officials can make evidence-based decisions about socializing, or opening offices and schools. His plan also pledges to enhance data analysis at hospitals and health departments, and to modernize data systems used within the US healthcare system, which are often painfully outdated…

Chasing an ambitious goal of administering 100 million shots to US residents in its first 100 days in office, the Biden team proposes 100 new vaccination centers run by the federal government, mobile vaccination units in underserved areas, and using grocery stores and stadiums as vaccination venues. The ramp-up includes growing the ranks of vaccinators with retired or foreign-trained doctors, as well as medical students, and by directing federal staff like nurses, physician assistants and doctors at various federal agencies to assist US states.” (D)

“Amazon is offering its help to President Joe Biden with the rollout of COVID-19 vaccines, while seeking to get its employees inoculated “at the earliest appropriate time.”

In a letter written to Biden and dated Wednesday, Amazon Worldwide Consumer CEO Dave Clark said the e-commerce giant is prepared to leverage its operations to help vaccinate 100 million Americans in the first 100 days of the president’s administration.

“Our scale allows us to make a meaningful impact immediately in the fight against COVID-19, and we stand ready to assist you in this effort,” wrote Clark.” (F)

“Amazon wrote to President Biden on Thursday offering to assist with communication and technology. Microsoft is opening up its largely empty office campus as a vaccination center as part of a broader partnership with the State of Washington. Starbucks is assigning workers from its operations and analytics departments to help design vaccination sites, donating the labor to the same state while continuing to pay employees.

While some retailers and pharmacy chains have been directly involved in the rollout of coronavirus vaccinations, more surprising is the number of companies that have offered help despite having little to do with health care.

What these companies do have are vast national footprints, significant manpower, huge distribution warehouses and, in some cases, empty office buildings. And they have the money to spare for a public service effort that could boost both their public image and their bottom line.

“Big companies can think big,” said Arthur Herman, senior fellow at the Hudson Institute, a think tank in Washington, D.C. “They can afford to step back and think about their role as a social force in their state and in the country. They also have enormous supply chains and logistical connections.”

As Mr. Biden tries to ramp up vaccination efforts, he will need all the help he can get. The president has asked Congress for $20 billion to help fund vaccinations at stadiums, pharmacies and the like. He said Friday that he had tapped the Federal Emergency Management Agency to operate up to 100 mass vaccination sites.

But the private sector could assist the administration’s efforts with data storage, appointment scheduling, the delivery of supplies to clinics and hospitals, and more.

“Amazon, Google, Microsoft, these guys are consumer-facing people who can deal with billions of transactions on a daily basis,” said Suketu Gandhi, a partner Kearney, a management and consulting firm.

Washington’s governor, Jay Inslee, included the help of companies like Starbucks, Costco and Microsoft in a plan to vaccinate 45,000 residents a day.

“We are not a health care company,” Kevin Johnson, the chief executive of Starbucks, said at a news conference announcing the partnership on Monday, “but Starbucks does operate 33,000 stores at scale, serving 100 million customers a week. And we have a world-class team of human-centered-design engineers who are working under the direction of the state, and health care providers like Swedish, Kaiser Permanente and others.”

The coffee chain will lend its expertise in “operational efficiency,” among other things, Governor Inslee said in a news release.

Microsoft will open up an empty building on its campus in Redmond to vaccinations in partnership with the state and health care providers. It is also offering its technology, building on abilities it has already offered to the government, including artificial intelligence to the State Department of Health to help track hospitalizations and tests.

“Certainly technology plays a role in the distribution of vaccines, as it basically does in the distribution of everything in the world,” Microsoft’s president and chief legal officer, Brad Smith, said at the event announcing the rollout.

Amazon is holding a pop-up vaccine clinic in Seattle on Sunday, through a partnership with Virginia Mason Medical Center; they hope to vaccinate 2,000 people. The company has also offered to vaccinate its own employees in the state, many of whom it says are essential workers — an offer it has made to Tennessee as well.” (G)

“As many as 90,000 Americans are projected to die from the coronavirus in the next four weeks, the Biden administration warned in its first science briefing on the COVID-19 pandemic, as experts outlined efforts to improve the delivery and injection of COVID-19 vaccines.

The hourlong briefing Wednesday by the team charged by President Joe Biden with ending the pandemic, was meant to deliver on his promise of “leveling” with the American people about the state of the outbreak that has already claimed more than 425,000 U.S. lives. It marked a sharp contrast from what had become the Trump show, in the last administration, when public health officials were repeatedly undermined by a president who shared his unproven ideas without hesitation.

The striking deaths projection wasn’t much different from what Biden himself has said, but nonetheless served as a stark reminder of the brutal road ahead.

Wednesday’s briefing was conducted virtually, rather than in person at the White House, to allow for questions from health journalists and to maintain a set timing no matter the situation in the West Wing. But it was not without technical glitches.

It featured Jeff Zients, the Biden administration’s coordinator for pandemic response; his deputy, Andy Slavitt; Dr. Anthony Fauci, the nation’s top infectious disease expert; Dr. Marcella Nunez-Smith, the chair of Biden’s COVID-19 equality task force, and Dr. Rochelle Walensky, the director of the Centers for Disease Control and Prevention.

“The White House respects and will follow the science, and the scientists will speak independently,” said Slavitt.” (I)

Contemporaneous Case Study methodology

Jonathan M. Metsch, Dr.P.H.

https://www.mountsinai.org/profiles/jonathan-m-metsch

POSTS 116, 117 & 118…….. POST 118. January 24, 2021. CORONAVIRUS. “Unfortunately, we’ve let this virus spread extensively and are launching the vaccination campaign at the height of the threat,”… “The more the virus spreads before the vaccine reaches people, the fewer deaths we can prevent with the vaccine.”

POSTS 116, 117 & 118…….. POST 118. January 24, 2021. CORONAVIRUS. “Unfortunately, we’ve let this virus spread extensively and are launching the vaccination campaign at the height of the threat,”… “The more the virus spreads before the vaccine reaches people, the fewer deaths we can prevent with the vaccine.”

“The coronavirus pandemic in the United States has raged almost uncontrollably for so long that millions of vaccinations will not be able to stop the spread of the disease unless people continue to wear masks and maintain social distancing measures until midsummer or later…

The arrival of highly effective vaccines in December lifted hopes that they would eventually slow or stop the spread of the disease through the rest of the population. But vaccines alone are not enough, the model shows. And if precautions like working remotely, limiting travel and wearing masks are relaxed too soon, it could mean millions more infections and thousands more deaths….

POST 117. January 23, 2021. CORONAVIRUS. 1.Dr. Fauci:“The idea that you can get up here….”and.. let the science speak”… “It is somewhat of a liberating feeling.” 2.updated CDC guidance:”.. providers could give the second dose up to six weeks after the first dose..” 3.Dr. Fauci: people would be “taking a chance” if they follow the CDC’s updated guidance.

“In rare circumstances, it’s OK for people to receive one shot of Pfizer’s Covid-19 vaccine and one shot of Moderna’s vaccine at least 28 days apart, the CDC said in updated guidance.

“U.S. health authorities said it is OK to delay second doses of Covid-19 vaccines up to six weeks after the first injection, which for some shots would be twice as long as recommended.

POST 116. January 22, 2021. President Biden – “We’re entering what may be the toughest and deadliest period of the virus. We must set aside politics and finally face this pandemic as one nation.”

“Twelve minutes before noon on Wednesday, President Joe Biden was sworn into office as the nation’s 46th president. Seven hours later, the United States reported more than 4,409 new deaths from the novel coronavirus, according to data collected by the COVID-19 Tracking Project.

The Biden administration came into power with purpose and an extensive agenda to combat the coronavirus pandemic, but purpose and planning only gets you so far—particularly when the president’s team is only just now getting a clear picture of how badly the previous administration had managed the crisis.

Doctor, Did You Wash Your Hands?®  at  https://doctordidyouwashyourhands.com/

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Contemporaneous Case Study methodology

Jonathan M. Metsch, Dr.P.H.

https://www.mountsinai.org/profiles/jonathan-m-metsch