“CDC urges faster testing to find human bird flu cases”

By Erika Edwards“

The Centers for Disease Control and Prevention on Thursday urged labs nationwide to determine within 24 hours of admission whether people hospitalized with the flu have seasonal influenza or are infected with the bird flu that’s behind an escalating outbreak in dairy cows and poultry.”to read the full article go tohttps://www.nbcnews.com/health/health-news/cdc-urges-faster-testing-find-human-bird-flu-cases-rcna187870

“CDC urges doctors to speed subtyping of patients hospitalized with the flu to better track H5N1 infections”
By Brenda Goodman, CNN
https://www.cnn.com/2025/01/16/health/cdc-urges-doctors-to-speed-subtyping-h5n1-infections/index.html?cid=ios_app

“Accelerated Subtyping of Influenza A in Hospitalized Patients”
Distributed via the CDC Health Alert Network

“CDC has routinely recommended influenza testing for hospitalized patients with suspected influenza. In light of the ongoing avian influenza A(H5) virus animal outbreak in the United States, CDC now recommends subtyping of all influenza A virus-positive specimens from hospitalized patients on an accelerated basis. This accelerated subtyping is part of a comprehensive strategy to identify severe human infections with avian influenza A(H5) viruses, in addition to characterizing seasonal influenza viruses in a timely fashion.”

to read the full press release go to
https://www.cdc.gov/han/2025/han00520.html

“White House’s Pandemic Office, Busy With Bird Flu, May Shrink Under Trump”
By Brian Bennett

“By Inauguration Day on Monday, most of the pandemic office’s staff will have cleared out their desks. The office, officially known as the Office of Pandemic Preparedness and Response Policy, or OPPR, is losing more than half of its 18-person staff as the Biden Administration hands off the duties to a Trump Administration that has yet to fill multiple key pandemic-response positions, according to two Biden Administration officials. “

to read the full article go to
https://time.com/7207599/trump-bird-flu-pandemic-office/

“Bird Flu Is Raising Red Flags Among Health Officials”

By Public Health On Call

“In this Q&A, adapted from the January 14 episode of Public Health On Call, Stephanie Desmon speaks with Meghan Davis, DVM, PhD ’12, MPH ’08, associate professor in Environmental Health and Engineering, and Andrew Pekosz, PhD, professor in Molecular Microbiology and Immunology, about why it’s time to double down on efforts to limit H5N1 transmission among cattle and birds, concerns about cats and other mammals, and how to prevent the virus from gaining a foothold in humans.”

to read the full article go to
https://publichealth.jhu.edu/2025/bird-flu-is-raising-red-flags-among-health-officials

“How Worried to Be About Bird Flu”
By Lora Kelley

“Lora Kelley: We last spoke in April, after a dairy worker became infected with bird flu. At the time, you described your level of concern about bird flu as “medium.” How would you describe your level of worry now?
Katherine J. Wu: At this point, I would upgrade it to “medium-plus.” I don’t think I will upgrade to “high” unless we start to see strong evidence of human-to-human transmission. I am not ruling out that possibility, but we aren’t there yet.”
to read the full article go to
https://www.theatlantic.com/newsletters/archive/2025/01/how-worried-to-be-about-bird-flu/681331/

“CDC tests confirm another H5N1 case from California”
By Lisa Schnirring

“The US Centers for Disease Control and Prevention (CDC) today confirmed another human H5N1 avian flu case in California, which likely reflects follow-up testing of a presumed positive involving a San Francisco child. The latest confirmation puts the national total since early 2024 to 67 cases, of which 38 are from California.”

to read the full article go to
https://www.cidrap.umn.edu/avian-influenza-bird-flu/cdc-tests-confirm-another-h5n1-case-california

“Why not making bird flu vaccines available now is a mistake”
By Leana S. Wen

“The good news is that the same companies that made those original vaccines have updated them and already manufactured about 5 million doses of the updated vaccines, and that the administration has contracted with them to produce another 5 million by this spring. Ten million shots of a two-dose vaccine won’t come close to meeting demand if bird flu became a pandemic, but in that horrific situation, the virus likely will have evolved further, and a new vaccine would have to be developed anyway. The initial 10 million can at least be used for those at highest risk.”

to read the full article go to
https://www.washingtonpost.com/opinions/2025/01/16/biden-bird-flu-vaccine-fda/

“How would RFK Jr. handle bird flu? His record on vaccines has experts on edge”
By Will Stone

“The incoming Trump administration will have to prepare for this risk. As H5N1 spills into more people and animals, scientists warn it could evolve to better infect humans and become more dangerous.
Trump and his picks to helm federal health agencies have largely been silent on bird flu. The messaging so far — and the track record of those Trump has chosen to oversee a potential bird flu crisis — is “worrisome,” says Dr. Andrew Pavia, professor of medicine at the University of Utah who’s worked on influenza pandemic preparedness for more than two decades.”

to read the full article go to
https://www.npr.org/sections/shots-health-news/2025/01/16/nx-s1-5254733/trump-cabinet-picks-rfk-bird-flu

“Age of the panzootic: scientists warn of more devastating diseases jumping between species”

By Phoebe Weston

“Bird flu poses a threat that is “unique and new in our lifetime” because it has become a “‘panzootic” that can kill huge numbers across multiple species, experts warn. For months, highly pathogenic bird flu, or H5N1, has been circulating in dairy farms, with dozens of human infections reported among farm workers. It has now jumped into more than 48 species of mammals, from bears to dairy cows, causing mass die-offs in sea lions and elephant seal pups. Last week, the first person in the US died of the infection.
This ability to infect, spread between, and kill such a wide range of creatures has prompted some scientists to call H5N1 a “panzootic”: an epidemic that leaps species barriers and can devastate diverse animal populations, posing a threat to humans too. As shrinking habitats, biodiversity loss and intensified farming create perfect incubators for infectious diseases to jump…”
to read the full article go to
https://www.theguardian.com/environment/2025/jan/15/age-of-the-panzootic-scientists-warn-of-more-devastating-diseases-jumping-between-species-aoe

“Bird flu is mutating, but antivirals still work for now”

by Texas Biomedical Research Institute

“One of the earliest strains of bird flu isolated from a human in Texas shows a unique constellation of mutations that enable it to more easily replicate in human cells and cause more severe disease in mice compared to a strain found in dairy cattle, researchers from Texas Biomedical Research Institute (Texas Biomed) report in Emerging Microbes & Infections.
The finding highlights a key concern about the H5N1 strains of bird flu currently circulating in the U.S.: the speed at which the virus can mutate when introduced to a new host.”
“”The clock is ticking for the virus to evolve to more easily infect and potentially transmit from human to human, which would be a concern,” said Texas Biomed Professor Luis Martinez-Sobrido, Ph.D., whose lab specializes in influenza viruses and has been studying H5N1 since the outbreak began last year. The team has developed specialized tools and animal models to test prophylactic vaccines and therapeutic antivirals.”
to read the full article go to
https://www.telegraph.co.uk/global-health/science-and-disease/why-mild-h5n1-bird-flu-cases-have-been-perplexing-scientist/

“Trump and Biden officials begin talks on bird flu crisis”

By Berkeley Lovelace Jr., Erika Edwards and Suzy Khimm

“Amid an escalating bird flu outbreak spreading in the United States, federal health officials have begun to brief members of the incoming Trump administration about how they’ve responded to the crisis so far.
“We sent them all of the information on our work,” said a Biden administration health official familiar with transition briefings within the Centers for Disease Control and Prevention.
It’s the first indication that the two administrations appear to be working together to prioritize the H5N1 response.

to read the full article go to
https://www.nbcnews.com/health/health-news/trump-biden-bird-flu-crisis-meeting-transition-rcna187190

“Biden administration allocates $306m in its final days for bird flu response”

By Melody Schreiber

“Awarding funding to regional, state and local health departments is particularly important because “that seems to be an important catalyst to take action”, said Jennifer Nuzzo, professor of epidemiology and director of the Pandemic Center at Brown University School of Public Health.
“It’s often federal action of some sort, usually in the form of money, that gets states activated,” Nuzzo added.
Improving communication and data-sharing between local entities like healthcare professionals, businesses and school leaders is key for understanding patterns of disease in communities, Ranney said: “Who’s getting sick from what, when and why?””
to read the full article go to
https://www.nbcnews.com/health/health-news/trump-biden-bird-flu-crisis-meeting-transition-rcna187190

“Should we be panicked about bird flu? William Hanage says not yet.”

By Alvin Powell

““A key thing that we’ve not seen in the case of H5N1 and cattle are superspreading events.””
“We will certainly see another flu pandemic. That’s not an “if”; it’s a “when.” We cannot say how severe it will be, but we can say that it has the potential to be bad. We don’t talk enough about how we would detect it early and what we would do when it happens.”
“Are we doing enough with bird flu right now?
No. I would like to see more thorough investigation of the potential for transmission. I would like to see more careful surveillance of the adapting virus. I would like to understand more about the nature of the infections in the people we’ve identified them in.”
to read the full article go to
https://news.harvard.edu/gazette/story/2025/01/should-we-be-panicked-about-bird-flu-william-bill-hanage/

No, we’re not ‘one mutation away’ from an H5N1 bird flu pandemic. Here are the facts
by Ignacio López-Goñi and Elisa Pérez Ramíre

“Public health efforts should continue to focus on protecting workers exposed to infected animals with preventative measures, such as vaccination, to minimize risk. It is essential to investigate each human case to swiftly detect any changes that may suggest increased virulence or human-to-human transmissibility.
In addition, research into new therapeutic strategies and the development of universal vaccines (i.e. those effective against all influenza subtypes) remain a priority. We are not one mutation from a pandemic, but the H5N1 virus is certainly not getting any further away.”

to read the full article go to
https://medicalxpress.com/news/2025-01-mutation-h5n1-bird-flu-pandemic.html

“How the US is preparing for a potential bird flu pandemic”
By Jessica Hamzelou
“The good news is that there are already systems in place for tracking the general spread of flu in people. The World Health Organization’s Global Influenza Surveillance and Response System collects and analyzes samples of viruses collected from countries around the world. It allows the organization to make recommendations about seasonal flu vaccines and also helps scientists track the spread of various flu variants. That’s something we didn’t have for the covid-19 virus when it first took off.
We are also better placed to make vaccines. Some countries, including the US, are already stockpiling vaccines that should be at least somewhat effective against H5N1 (although it is difficult to predict exactly how effective they will be against some future variant). The US Administration for Strategic Preparedness and Response plans to have “up to 10 million doses of prefilled syringes and multidose vials” prepared by the end of March, according to an email from a representative.
If we want our vaccine production process to be more robust and faster, we’ll have to stop relying on chicken eggs.”
to read the full article go to
https://www.preventionweb.net/news/how-us-preparing-potential-bird-flu-pandemic

H5N1: How worried should we be?
By Nora Samaranayake
https://www.usf.edu/health/news/2025/h5n1-update.aspx

“NYC Health + Hospitals/Bellevue to Receive $2M of Federal Funding to Advance Avian Flu Preparedness” (Press Release)

“NYC Health + Hospitals/Bellevue today announced it will receive $2 million from the federal government to enhance national avian influenza preparedness, one of only thirteen institutions nationwide to receive this funding. Bellevue Hospital is the designated Regional Emerging Special Pathogen Treatment Center (RESPTC) for Region 2, leading special pathogen preparedness and response efforts in New York, New Jersey, Puerto Rico, and the U.S. Virgin Islands.”
Health care and ambulance workers needed to wear an N95 respirator, eye protection, gown and gloves and follow strict protocols to ensure their safety while handling the patient to prevent exposure to the simulated pathogen.
“As part of NETEC and as the Level 1 RESPTC for Region 2, Bellevue Hospital understands that effective response requires both expertise and extensive coordination,” said Vikramjit Mukherjee, MD, NETEC Co-Principal Investigator, and Director of the Special Pathogens Program and Director of Critical Care Services at NYC Health + Hospitals/Bellevue. “Our established relationships with Special Pathogens Treatment Centers (SPTCs) and frontline facilities ensure that we can rapidly disseminate critical protocols and training to healthcare systems and emergency preparedness partners across the country.””
“NYC Health + Hospitals/Bellevue was one of three institutions in the U.S. that treated patients in the Ebola outbreak in 2014, and subsequently formed the National Emerging Special Pathogens Training and Education Center (NETEC), a consortium to enhance national special pathogen preparedness. The other two institutions are Emory University in Atlanta and University of Nebraska Medical Center/Nebraska Medicine in Omaha, Nebraska. For more about NETEC, avian flu training and resources, or to request technical assistance, visit NETEC.org.”

to read the full press release go to
https://www.nychealthandhospitals.org/pressrelease/nyc-health-hospitals-bellevue-to-receive-2m-of-federal-funding-to-advance-avian-flu-preparedness/

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Falling Child Vaccinations
https://www.nytimes.com/2025/01/13/briefing/childhood-vaccinations-trump.html?smid=nytcore-ios-share&referringSource=articleShare
Even Adults May Soon Be Vulnerable to ‘Childhood’ Diseases
https://www.nytimes.com/2025/01/13/health/vaccines-children-measles-pertussis.html?smid=nytcore-ios-share&referringSource=articleShare
How Lagging Vaccination Could Lead to a Polio Resurgence
https://www.nytimes.com/2025/01/13/health/polio-vaccine-outbreaks.html?smid=nytcore-ios-share&referringSource=articleShare
Childhood Vaccination Rates Were Falling Even Before the Rise of R.F.K. Jr.
https://www.nytimes.com/interactive/2025/01/13/upshot/vaccination-rates.html?smid=nytcore-ios-share&referringSource=articleShare

“First US human death from bird flu is more serious than you may think”

By Bronwyn Thompson

“…..Post-infection mutation and no human-to-human transmission suggests whatever the viral changes, it’s not one that hugely concerns epidemiologists. It would be far worse for someone to become infected with an already altered H5N1 D1.1 strain, which would most likely point to the virus getting closer to cracking the complex code of human-to-human infection.
“The worry is, the more you let this sort of run wild … the more chances you have for this sort of mutation to not only occur, but to then get out and infect someone else, then you start a chain reaction,” Louisiana State University scientist Rebecca Christofferson told AFP this week.”…
“Further analysis identified that the mutation has the potential to more efficiently bind to cells in the upper respiratory tract in humans, which existing avian influenza strains have been unable to do. And, obviously, experts are concerned that each time the virus proves more adept at causing severe human infection, the more likely it will also figure out how best to jump between people.”
to read the full article go to
https://newatlas.com/infectious-diseases/first-us-human-death-bird-flu/

“Bird Flu Is a National Embarrassment. America should have more aggressively intervened almost a year ago.”

By Katherine J. Wu

“Three years ago, when it was trickling into the United States, the bird-flu virus that recently killed a man in Louisiana was, to most Americans, an obscure and distant threat…..But this virus is fundamentally more difficult to manage than even a few months ago and is now poised to become a persistent danger to people.
“That didn’t have to be the reality for the United States. “The experiment of whether H5 can ever be successful in human populations is happening before our eyes,” Seema Lakdawala, a flu virologist at Emory University, told me. “And we are doing nothing to stop it.” The story of bird flu in this country could have been shorter. It could have involved far fewer cows. The U.S. has just chosen not to write it that way.”
to read the full article go to
https://www.theatlantic.com/health/archive/2025/01/bird-flu-embarrassing/681264/

“California child is presumed positive for bird flu”
https://www.cnn.com/2025/01/10/health/california-child-bird-flu/index.html?cid=ios_app

“Bird flu will be the next pandemic unless health officials take 6 critical steps, experts say”


BY Carolyn Barber
“This is how pandemics start,” Rick Bright, the renowned immunologist, vaccine researcher and former federal health official, tells Fortune. “We’ve had months to prepare, to activate and expand surveillance, to educate people about the risk, and even to make vaccines available that can help to reduce the risk of the current form of the virus.
“I hope that this death is not minimized or blamed on underlying medical conditions,” Bright adds. “The virus is changing quickly. We need to step up the pace of all efforts to track it and update our medical countermeasures to be ready when it pops.”
to read the full article go to
https://fortune.com/well/2025/01/09/bird-flu-next-pandemic-steps-prevent-spread/

“As 1st bird flu death reported in US, what could happen with virus in 2025.”
By Mary Kekatos
“Dr. Peter Hotez, co-director of the Texas Children’s Hospital Center for Vaccine Development and dean of the National School of Tropical Medicine at Baylor College of Medicine, said he believes there is a more likely scenario of the virus becoming more transmissible: an individual getting infected with bird flu and seasonal influenza at the same time.?
He said this could lead to the virus “reassorting” to produce a hybrid, or recombinant, virus that could then transmit more easily from person to person.”
to read the full article goto
https://abcnews.go.com/Health/1st-bird-flu-death-reported-us-happen-virus/story?id=117417561

“Is bird flu the next pandemic? What to know after the first H5N1 death in the US”
By Brenda Goodman
“Scientists think H5N1 infects the eyes because flu viruses enter cells through sugars on their surface called sialic acids. Birds – and human eyes – primarily have alpha 2,3 sialic acid receptors on their cells. But a different kind of sialic acid receptor, alpha 2,6, is more prevalent in the human respiratory tract. Human flu viruses, including those that cause seasonal influenza, have evolved to infect cells through alpha 2,6 receptors.
Given enough time in the human body, the bird flu virus has shown the ability to change to become better at infecting different kinds of cells and tissues, spreading from the eyes to the respiratory tract, for example.”
to read the full article go to
https://www.cnn.com/2025/01/08/health/bird-flu-h5n1-pandemic-risk-explained/index.html?cid=ios_app

“US to build new stockpile of bird flu vaccine for poultry”
By Leah Douglas and Tom Polansek
“Agriculture Secretary Tom Vilsack has said such deployment would not be possible in the short term, in part due to trade risks. Many countries ban imports of vaccinated poultry over concerns the vaccine could mask the presence of the virus.”
to read the full article go to
https://www.reuters.com/business/healthcare-pharmaceuticals/us-build-new-stockpile-bird-flu-vaccine-poultry-2025-01-08/

“What We Know About HMPV, the Common Virus Spreading in China”
https://www.nytimes.com/2025/01/07/health/hmpv-virus-china.html?smid=nytcore-ios-share&referringSource=articleShare